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A simpler path to answers for patients with mast cell activation syndrome featured image
A simpler path to answers for patients with mast cell activation syndrome

A random urine test panel aids in diagnosing mast cell activation syndrome (MCAS), a complex condition often misdiagnosed due to overlapping symptoms. The panel improves access, speeds up diagnosis, and enables individualized treatment by detecting key mast cell mediators.

August 11, 2025
Last chance to register for virtual phlebotomy workshop featured image
Last chance to register for virtual phlebotomy workshop
September 10, 2025

The registration deadline for Mayo Clinic Laboratories Education’s first-ever virtual phlebotomy workshop on Oct. 1 is fast approaching. Register today.

Join us on Oct. 29 for a SAAmplify-αSYN testing webinar featured image
Join us on Oct. 29 for a SAAmplify-αSYN testing webinar
September 8, 2025

Join us for a webinar exploring the revolutionary way SAAmplify™–αSYN testing, which is offered by Mayo Clinic Laboratories in collaboration with Amprion, is improving diagnostic accuracy for patients with neurodegenerative disorders.

A woman visits a patient in a hospital bed.
Back to School: Teaching Others to See and Report Safety in the Workplace
September 8, 2025

Review five crucial patient safety practices that everyone can utilize to promote patient safety.

Avian Flu Outbreaks and New COVID-19 Variants: Matthew Binnicker, Ph.D. featured image
Avian Flu Outbreaks and New COVID-19 Variants: Matthew Binnicker, Ph.D.
May 23, 2024

In this episode of “Answers From the Lab,” host Bobbi Pritt, M.D., chair of the Division of Clinical Microbiology at Mayo Clinic, is joined by Matthew Binnicker, Ph.D., professor of laboratory medicine and pathology and clinical virologist at Mayo Clinic. They discuss the widespread outbreaks of H5N1 bird flu and the new “FLiRT” variants of COVID-19.

A lab technician in protective gear handles a cart filled with colorful test tubes.
Establishing a trusted lab partner in an evolving landscape
May 22, 2024

William Morice II, M.D., Ph.D., president and chief executive officer of Mayo Clinic Laboratories, authored a Becker’s Healthcare article on how hospital laboratories can navigate times of change and uncertainty with the steadfast support of a business partner like Mayo Clinic Laboratories.

A woman wearing glasses looks through a microscope in a laboratory.
Mayo Clinic Laboratory and Pathology Research Roundup: May 21
May 21, 2024

This week's research roundup feature: Monoclonal immunoglobulin (MIg) crystalline nephropathies are rare lesions resulting from precipitation of MIgs in the kidney as crystalline inclusions. They can be categorized into lesions with predominant intracellular crystals (light chain [LC] proximal tubulopathy, LC crystal-storing histiocytosis, LC crystalline podocytopathy] and lesions with predominant extracellular crystals (crystalglobulin-induced nephropathy, crystalline variant of LC cast nephropathy).

Enhanced Solid Tumor NGS Panel Broadens Genetic-Variants Detection: Robert Jenkins, M.D., Ph.D., Stephanie Smoley, CG(ASCP), and Beth Pitel, M.S. featured image
Enhanced Solid Tumor NGS Panel Broadens Genetic-Variants Detection: Robert Jenkins, M.D., Ph.D., Stephanie Smoley, CG(ASCP), and Beth Pitel, M.S.
May 21, 2024

Robert Jenkins, M.D., Ph.D., Stephanie Smoley, CG(ASCP), and Beth Pitel, M.S., explain how Mayo Clinic Laboratories' enhanced MayoComplete Solid Tumor Panel better profiles tumor genetics. Defining tumor pathogenesis can guide targeted cancer therapy.

A gloved hand holds a test tube with yellow liquid beside a microscope.
Managing patient expectations for home specimen collection
May 20, 2024

When patients are tasked with collecting specimens at home, the procedure can require special timing, collection steps, or storage conditions. If these aren’t clearly communicated to the patient beforehand, it can lead to confusion and unnecessary frustration. A laboratory can set up its patients for success by managing expectations when home collections are necessary. These steps can help ensure a successful experience for both patients and laboratory staff.

Breathing Easier: Immunotherapies for Asthma and Allergy featured image
Breathing Easier: Immunotherapies for Asthma and Allergy
May 17, 2024

In this episode of “Lab Medicine Rounds,” host Justin Kreuter, M.D., interviews Douglas McMahon, M.D., from the Allergy and Asthma Center of Minnesota, to discuss how the lab supports asthma and allergy medical practice.

An older man and woman smiling and holding hands while walking on a tree-lined street.
New Panels Help Find Cause of Rapidly Progressive Dementia: Gregg Day, M.D.
May 14, 2024

Rapidly progressive dementia (RPD) is an umbrella term covering many devasting conditions, including Creutzfeldt-Jakob disease (CJD). Gregory (Gregg) Day, M.D., explains how Mayo Clinic Laboratories' unique RPD evaluation and new CJD test help pinpoint diagnosis, to guide prognosis and treatment decisions.

A scientist uses a pipette in a lab with a colorful DNA sequence display in the background.
Mayo Clinic Laboratory and Pathology Research Roundup: May 14
May 14, 2024

This week's research roundup feature: Despite advances in understanding the genetic abnormalities in myeloproliferative neoplasms (MPNs) and the development of JAK2 inhibitors, there is an urgent need to devise new treatment strategies, particularly for triple negative myelofibrosis (MF) patients who lack mutations in the JAK2 kinase pathway and have very poor clinical outcomes.

Red boxes labeled Mayo Clinic Laboratories on a conveyor belt.
Memorial Day 2024 Specimen Shipping Guidelines and Schedule
May 13, 2024

Mayo Clinic Laboratories specimen pickup and delivery schedules will be altered due to the upcoming Memorial Day holiday on Monday, May 27, 2024. To ensure specimen stability and prevent delays, follow the guidelines below outlined for domestic clients and international clients.

Infectious disease test gains U.S. FDA approval featured image
Infectious disease test gains U.S. FDA approval
May 13, 2024

An ideal testing partner will offer extensive expertise in assay development and analytical validation services, along with access to biospecimens. In this collaboration example, learn how Mayo Clinic Laboratories’ BioPharma Diagnostics team helped a musculoskeletal diagnostics company complete a prospective study to demonstrate its test’s performance in detecting periprosthetic joint infection (PJI) in synovial fluid.

Close-up of lab equipment handling multiple laboratory samples.
Get to Know the DLMP Chair: Eric Hsi, M.D.
May 9, 2024

In this episode of “Answers From the Lab,” host Bobbi Pritt, M.D., chair of the Division of Clinical Microbiology at Mayo Clinic, is joined by Eric Hsi, M.D., chair of the Department of Laboratory Medicine and Pathology at Mayo Clinic.

Paul Jannetto, Ph.D., contributes to landmark discovery of Beethoven’s hair lead concentration featured image
Paul Jannetto, Ph.D., contributes to landmark discovery of Beethoven’s hair lead concentration
May 9, 2024

In a landmark discovery published in Clinical Chemistry, authenticated locks of hair from the composer Ludwig van Beethoven have revealed high lead concentrations after being analyzed at Mayo Clinic. Paul Jannetto, Ph.D., director of the Metals Laboratory at Mayo Clinic, along with his laboratory staff, completed testing on two independent and authenticated locks of Beethoven’s hair which confirmed the presence of high lead concentrations and could explain the cause for many of Beethoven’s ailments.

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