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A Mayo Pathologist’s Journey through Paraneoplastic Syndrome and a Double Lung Transplant: Dr. Brad Karon

After mysterious neurological symptoms began in 2010, Brad Karon, M.D., Ph.D., was diagnosed with paraneoplastic syndrome, a rare condition that led to groundbreaking research and test development at Mayo Clinic. Years later, pulmonary fibrosis and a double lung transplant would test him once again — and redefine his resilience.

July 21, 2025
Dr. Bill Morice offers data-driven reasons to retain lab services
August 5, 2025

William Morice II, M.D., Ph.D., highlights data-driven reasons health systems benefit from the lab service line and strategies to bolster performance.

Transformative Feedback: How to Overcome the Summer Slump
August 4, 2025

Review the art of delivering clear, constructive feedback; tips for navigating potentially challenging conversations with respect; highlighting the importance of positive feedback.

Toxicology Transformed: From Opioids to Saliva — A Chemistry-Centric Journey
August 1, 2025

As drug trends and diagnostic technologies evolve, toxicology must adapt to meet the demands of healthcare, workplace safety, and public health—focusing on opioid detection, CBD use, patient-centered testing, and new methods like saliva analysis, each bringing distinct challenges and opportunities. The following podcast episodes feature chemistry-related interviews that discuss these topics.

Leading diagnostics into the future: Dr. Bill Morice
September 19, 2022

William Morice II, M.D., Ph.D., chair of the Department of Laboratory Medicine and Pathology at Mayo Clinic and CEO and president of Mayo Clinic Laboratories, joins "Answers From the Lab" for his weekly leadership update with host Bobbi Pritt, M.D. In this episode, they discuss Dr. Morice’s new role as CEO and president of Mayo Clinic Laboratories (MCL), his patient-centered vision for the future, and how MCL is leading positive changes in the diagnostics industry.

Week in Review: September 16
September 16, 2022

Topic highlights include: Mayo Clinic health system experts say mental health issues on the rise, New York declares a state of emergency over polio, U.S. reaches medical milestone with millionth organ transplant

Advice for Medical Students Matching Into Pathology
September 16, 2022

In this episode of “Lab Medicine Rounds,” Justin Kreuter, M.D., sits down with Ann Moyer, M.D., Ph.D., associate professor of laboratory medicine and pathology, assistant professor[...]

PCD test provides definitive diagnosis of a rare disease
September 15, 2022

Joseph Maleszewski, M.D., and Marie-Christine Aubry, M.D., explain how Mayo Clinic Laboratory can provide definitive diagnosis of primary ciliary dyskinesia (PCD). Mayo Clinic's expertise and technology have earned the laboratory's designation as the sole center of excellence for diagnosing this rare respiratory disorder.

Phage immunoprecipitation sequencing identifies previously unknown disease biomarkers
September 14, 2022

In Mayo Clinic’s Advanced Diagnostics Laboratory, there are dozens of projects underway at once to develop new technologies, discover novel findings, validate new tests, and support physicians in providing advanced patient care. For example, researchers are using phage immunoprecipitation sequencing (PhIP-Seq) to discover new serological biomarkers for autoimmune diseases. In a recent study using PhIP-Seq, Mayo Clinic researchers discovered a previously unknown antibody marker for immune-mediated rippling muscle disease (iRMD). This finding will support testing options and accurate diagnosis of iRMD, helping physicians treat patients with iRMD and restore their quality of life.

Direct Ethanol Biomarker Testing: PETH
September 13, 2022

Paul Jannetto, Ph.D., describes Mayo Clinic Laboratories' new direct biomarker test for alcohol consumption. PETH is a blood test with a window of detection of about two to four weeks — compared with five days for urine-based screening for alcohol use.

Mayo Clinic Laboratory and pathology research roundup: September 13
September 13, 2022

This week's research roundup features: A simple score to identify increased risk of transthyretin amyloid cardiomyopathy in heart failure with preserved ejection fraction

Week in Review: September 9
September 9, 2022

Topic highlights include: Five ways you’ll exercise smarter in the future, Scientists discovered an antibody that can take out all COVID-19 variants, Mayo launches accelerator dedicated to gene and cell therapies

Looking at the big picture: Dr. Bill Morice
September 8, 2022

William Morice II, M.D., Ph.D., chair of the Department of Laboratory Medicine and Pathology at Mayo Clinic and CEO and president of Mayo Clinic Laboratories, joins "Answers From the Lab" for his weekly leadership update with host Bobbi Pritt, M.D. In this episode, Dr. Pritt and Dr. Morice discuss current challenges in lab medicine and what it means to be a laboratory leader, including innovation, test stewardship, and the use of digital pathology.

Darci Block, Ph.D., talks autoverification with CAP Today
September 7, 2022

Darci Block, Ph.D., co-director of the Central Clinical Lab in Mayo Clinic’s Department of Laboratory Medicine and Pathology in Rochester, Minnesota, discusses how and when autoverification is used and not used to help verify the approximately 8,000 specimens that are sent to the department’s Central Clinical Lab every day.

Dr. William Morice II and Mary Jo Williamson named leaders for Mayo Clinic diagnostic services to enhance, expand expertise
September 6, 2022

Two leaders have been announced to lead Mayo Clinic Laboratories and other diagnostic services in the biopharma and cardiovascular spaces. William Morice II, M.D., Ph.D., has been named CEO and president and Mary Jo Williamson has been named chief administrative officer.

Mayo Clinic Laboratory and pathology research roundup: September 6
September 6, 2022

This week's research roundup features: Outcomes of tricuspid valve repair with artificial neochordae in pediatric and adult patients

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