Controlled Substances

Register now –Nov. 11, 2026 Review the evidence supporting modern urine drug monitoring, compare immunoassay, definitive, and hybrid testing strategies, and provide practical guidance for selecting testing based on clinical scenarios

We’ve created two new oral fluid specimen collection videos for controlled substance monitoring. The first video is designed to support healthcare professionals by outlining how to safely and effectively oversee a patient’s specimen collection. The second is from the patient’s perspective, giving them a step-by-step guide for what to expect during the collection process.

Paul Jannetto, Ph.D., explains the advantages that Mayo Clinic Laboratories' oral fluid drug screening offers over typical urine tests. Oral samples are easier to collect and harder to adulterate.