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Mayo Clinic Laboratories > Dementia biomarker testing

Leading-edge Alzheimer’s disease dementia biomarker testing

Advancing Alzheimer’s disease research and discovery

Research into the role of fluid-based biomarkers for the assessment of brain amyloid beta (Aβ) pathology is quickly advancing the understanding of Alzheimer’s disease and related dementias. As fluid-based biomarkers redefine how Alzheimer’s disease is diagnosed — and how individuals are enrolled in clinical trials — incorporation of fluid biomarkers into clinical studies is crucial.

We infuse Mayo Clinic quality into our comprehensive menu of biomarker testing for Alzheimer’s disease and related dementias. This includes blood-biomarker testing developed by Mayo Clinic and our strategic laboratory partners, as well as a robust portfolio of cerebrospinal fluid biomarker testing. Available to support biopharmaceutical research initiatives, these tests can help investigators accelerate therapeutic discovery and deliver breakthrough treatments to patients more quickly.

Want to learn more about our testing advantages? Click here to access our ebook.

"These biomarkers are changing neurodegenerative clinical trials, making it simpler and faster to identify and stratify patients. Through these innovations, research teams can increase the number of patients successfully recruited and also potentially lower the cost of clinical trials. We’re excited to provide testing that opens up new options to support Alzheimer's disease clinical trials.”

Alicia Algeciras-Schimnich

Alicia Algeciras-Schimnich, Ph.D., Professor of Laboratory Medicine and Pathology and Co-Director of the Clinical Immunoassay Laboratory at Mayo Clinic Laboratories

The leading edge of biomarker testing

Our physician scientists are actively engaged in research into new Alzheimer’s disease-related biomarkers and attuned to emerging research trends about the impact of biomarker testing in order to develop the most clinically meaningful assays for both commercial and research purposes.

Among fluid-based biomarkers known to predict Aβ pathology, phosphorylated Tau 217 (p-Tau217) exhibits the highest levels of diagnostic accuracy.

Empowering research

Mayo Clinic Laboratories BioPharma Diagnostics is pushing the boundaries of Alzheimer’s disease research through the development of proactive blood biomarker testing that can identify Aβ pathology at a stage when lifestyle modifications and disease-modifying therapies are likely to be most effective. Beyond diagnosis, the ability of blood biomarker testing to stratify patient populations based on genetic profiles and pathological progression enables more efficient, targeted research trials.

Our digital resource examines the evolution of blood biomarker testing and explains how results from these evaluations power your research and clinical trials.

Download now

Fill out the form to download our digital guide on biomarker testing for Alzheimer’s disease and related dementias at Mayo Clinic Laboratories.

Dementia testing: Empowering research and the development pipeline


Collaborations that drive change

Addressing patient needs is at the center of what we do at Mayo Clinic Laboratories BioPharma Diagnostics, and our ties to Mayo Clinic physicians and scientists lend expert clinical leadership to every research project. Our team of medical, laboratory, and business professionals brings unmatched experience to support even the most complex projects. Working side-by-side with partners, we provide direct collaboration with our scientific and medical experts to help you achieve your research goals. Please get in touch — we look forward to discussing testing needs that support your dementia research program.


Resources
Clinical trials at Mayo Clinic utilizing fluid-based biomarkers (representative sampling)

Please visit our Clinical Trials page to find the full, current list of Alzheimer’s disease and dementia research studies underway at Mayo Clinic.