Mayo Clinic Laboratories > Gastroenterology > Pediatric > H. pylori

Helicobacter pylori

Streamlined evaluation for an easier experience

As the main cause of peptic ulcer disease and a major risk factor for gastric cancer, Helicobacter pylori, or H. pylori, requires treatment to prevent life-threatening medical conditions. Timely diagnosis is critical for improving outcomes and avoiding further harm. However, the rising prevalence of antimicrobial resistance presents a clinical challenge to physicians when deciding who to test and the best medication to treat bacterial infection.

4.4 billion

4.4 billion individuals globally are affected by H. pylori infection

35%-85%

35%-85% of children have H. pylori infection depending on their geographic region1,2

Helicobacter pylori Test menu

Helicobacter pylori Helicobacter pylori
Additional testing Additional testing

Helicobacter pylori

Our H. pylori assay provides a streamlined solution to the challenge of diagnosing and treating the infection by evaluating for both the bacteria and antimicrobial resistance through one noninvasive test. Especially suited for children, our assay is the only clinically available test of its kind and uses a single stool specimen to predict clarithromycin resistance.

Key testing

Advantages

  • Uses polymerase chain reaction to interrogate the three 23S ribosomal RNA gene mutations most often associated with clarithromycin resistance.
  • Enables results that can aid clinicians in determining the best therapy for eradicating H. pylori in each child.
  • Promotes antimicrobial stewardship.
Download now Mayo Clinic Laboratories’ H. pylori diagnostic algorithm can help determine who is a good candidate for these tests.

Highlights

Helicobacter pylori testing: 2021 update

In this month’s Hot Topic, Robin Patel, M.D., discusses Mayo Clinic Laboratories’ new PCR assay for detection of Helicobacter pylori detection and determination of clarithromycin resistance directly from stool.

Learn more

Additional testing

Key testing

References
  1. Hassan M, et al. Global prevalence of Helicobacter pylori and its effect on human health-Pakistan. Pure and Applied Biology. 2020:936–48.
  2. Zamani M, et al. Systematic review with meta-analysis: the worldwide prevalence of Helicobacter pylori infection. Aliment Pharmacol Ther. 2018 April; 47(7): 868-876. doi:10.1111/apt.14561. Epub 2018 Feb 12. PMID: 29430669.
INTERESTED IN LEARNING MORE?

Fill out the form below and one of our specialists will be in touch.