Providing clarity and actionable results

The diagnosis of bleeding and thrombosis disorders relies heavily on specialized coagulation assays, but genotype assays are increasing in utility and availability.

Next-generation sequencing (NGS) testing can provide useful information that assists physicians including:

• Confirming the diagnosis of bleeding and thrombosis disorders
• Providing clarity and actionable results in situations where other testing methodologies provide inconclusive results for patients
• Identifying mutations that could explain patients’ unusual hemostatic phenotype and laboratory results

Created to meet the growing needs of our own clinical practice, Mayo Clinic now offers a comprehensive NGS full-gene sequencing menu for patients who have bleeding and thrombosis disorders.

Key testing

ATNGS | Antithrombin Deficiency, SERPINC1 Gene, Next Generation Sequencing, Varies

F2NGS | Factor II Deficiency, F2 Gene, Next-Generation Sequencing

F5NGS | F5 Gene, Next-Generation Sequencing

F7NGS | Factor VII Deficiency, F7 Gene, Next-Generation Sequencing

F8NGS | Hemophilia A, F8 Gene, Next-Generation Sequencing

NGSF9 | Hemophilia B, F9 Gene, Next-Generation Sequencing, Varies

F10NG | Factor X Deficiency, F10 Gene, Next-Generation Sequencing

F11NG | Hemophilia C, F11 Gene, Next-Generation Sequencing

F12NG | F12 Gene, Next-Generation Sequencing

F13NG | Factor XIII Deficiency, F13A1 and F13B Genes, NextGeneration Sequencing

FIBNG | Congenital Fibrinogen Disorders, FGA, FGB, and FGG Genes, Next-Generation Sequencing

THBNG | THBD Gene, Next-Generation Sequencing

VWFNG | von Willebrand Disease, VWF Gene, Next Generation Sequencing

PCNGS | Protein C Deficiency, PROC Gene, Next-Generation Sequencing, Varies

PRSNG | Protein S Deficiency, PROS1 Gene, Next Generation Sequencing

PRCNG | PROCR Gene, Next-Generation Sequencing