The Research Roundup provides an overview of the past week’s research from Mayo Medical Laboratories consultants, including featured abstracts and complete list of published studies and reviews.
Autonomic dysfunction (AD) after allogeneic stem cell transplant (SCT) is a rare occurrence and likely immune-mediated in etiology. There is limited literature on this topic and Mayo Clinic researchers describe management of two cases at the institution and their outcomes. They retrospectively identified two patients with immune-mediated AD after SCT from their database. Immune-mediated AD was defined as AD secondary to an immune-mediated etiology without an alternative cause and responding to immunosuppression. Based on the results, AD after SCT is a rare yet significant clinical entity. A workup of underlying etiology should be performed. IVIG is a treatment option for these patients. The review was published in Case Reports in Hematology.