Mayo Clinic Laboratory and Pathology Research Roundup: Dec. 25

The Research Roundup provides an overview of the past week’s research from Mayo Medical Laboratories consultants, including featured abstracts and complete list of published studies and reviews.

Featured Abstract

Global Pulmonary Vascular Remodeling in Pulmonary Hypertension Associated with Heart Failure and Preserved or Reduced Ejection Fraction

Mayo Clinic researchers hypothesized that pulmonary venous hypertension in heart failure leads to predominate remodeling of pulmonary veins and that the severity of venous remodeling is associated with the severity of pulmonary hypertension in heart failure. Based on study results, researchers found that in heart failure, pulmonary hypertension is associated with global pulmonary vascular remodeling but the severity of pulmonary hypertension correlates most strongly with venous and small IV intimal thickening, similar to the pattern observed in primary pulmonary veno-occlusive disease. These findings expand our understanding of the pathobiology of pulmonary hypertension in heart failure. The study was published in Circulation.

Published to PubMed This Week

Kelley Luedke (@kschrib)

Kelley Luedke

Kelley Luedke is a Marketing Channel Manager at Mayo Clinic Laboratories. She is the principle editor and writer of Insights and leads social media and direct marketing strategy. Kelley has worked at Mayo Clinic since 2013. Outside of work, you can find Kelley running, traveling, playing with her kitty, and exploring new foods.