The Research Roundup provides an overview of the past week’s research from Mayo Medical Laboratories consultants, including featured abstracts and complete list of published studies and reviews.
Featured Abstract
Cardiovascular Concerns in BRCA1 and BRCA2 Mutation Carriers
BRCA1 and BRCA2 mutation carriers can be at increased cardiovascular risk. Mayo Clinic researchers conducted a review to provide information about factors associated with increased cardiovascular risk, methods to prevent cardiovascular toxicities, and recommended screening guidelines. BRCA1/2 mutation carriers who are diagnosed with cancer are often exposed to chemotherapy, chest radiotherapy, and/or HER2 directed therapies, all of which can be cardiotoxic. In addition, BRCA1/2 carriers often undergo prophylactic salpingoopherectomies, which may also increase cardiovascular risks. Understanding the potential for increased cardiovascular risk in individuals with a BRCA1 or BRCA2 mutation, as well as gold standard practices for prevention, detection, and treatment of cardiac concerns in this population, is important. The study was published in Current Treatment Options in Cardiovascular Medicine.
Published to PubMed This Week
-
-
-
-
- cIMPACT-NOW Update 2: Diagnostic Clarifications for Diffuse Midline Glioma, H3 K27M-Mutant and Diffuse Astrocytoma/Anaplastic Astrocytoma, IDH-Mutant
Acta Neuropathologica - Over-the-Counter "Adrenal Support" Supplements Contain Thyroid and Steroid-Based Adrenal Hormones
Mayo Clinic Proceedings - Perihilar Cholangiocarcinoma
Mayo Clinic Proceedings - Momelotinib Therapy for Myelofibrosis: A 7-Year Follow-Up
Blood Cancer Journal - Next-generation Sequencing Reveals Recurrent Somatic Mutations in Small Cell Neuroendocrine Carcinoma of the Uterine Cervix
American Journal of Surgical Pathology - U2AF1 Mutation Variants in Myelodysplastic Syndromes and Their Clinical Correlates
American Journal of Hematology - Longitudinal Treatment Outcomes for an Interdisciplinary Pain Rehabilitation Program: Comparisons of Subjective and Objective Outcomes Based on Opioid Use Status
Journal of Pain - Population-Based Incidence of Conjunctival Tumors in Olmsted County, Minnesota
British Journal of Ophthalmology - Neoplastic Embolization to Systemic and Pulmonary Arteries
Journal of Vascular Surgery - Prognostic Factors and Benefits of Adjuvant Therapy After Pancreatoduodenectomy for Ampullary Adenocarcinoma: Mayo Clinic Experience
European Journal of Surgical Oncology - Diagnosis and Monitoring of HCV Infection Using the Cobas HCV Test for Use on the Cobas 6800/8800 Systems
Journal of Clinical Virology
- cIMPACT-NOW Update 2: Diagnostic Clarifications for Diffuse Midline Glioma, H3 K27M-Mutant and Diffuse Astrocytoma/Anaplastic Astrocytoma, IDH-Mutant
-
-
-
