Darci Block, Ph.D., and Nikki Baumann, Ph.D, Featured in Clinical Biochemistry Journal

Dr. Nikola Baumann, Ph.D., (left) and Darci Block, Ph.D., Co-Directors of Mayo Clinic’s central clinical laboratory. Photo courtesy of CAP Today.

Darci Block, Ph.D., Director of Laboratory Services and Co-Director of the Central Clinical Laboratory at Mayo Clinic, and Nikki Baumann, Ph.D., Co-Director of the Central Clinical Laboratory and Director of the Central Processing Laboratory at Mayo Clinic, were recently published in Clinical Biochemistry for their manuscript, “An Approach to Analytical Validation and Testing of Body Fluid Assays for the Automated Clinical Laboratory.”

Biochemical analysis of body fluids may lend insight into the pathogenesis of disease. Most commercially available clinical laboratory methods are intended for blood-derived specimens and/or urine and laboratories must characterize the analytical performance of these methods for other specimen types such as body fluids. In their research, Drs. Block and Baumann aimed to demonstrate one approach for characterizing analytical performance of assays for clinical analysis of body fluids.

The team assessed accuracy, precision, analytical measurable range, reportable range, analytic sensitivity, interferences, and analyte stability. Laboratory workflow for body-fluid handling was designed based on these results.

Read the full article.

Kelley Luedke

Kelley Luedke is a Marketing Channel Manager at Mayo Clinic Laboratories. She is the principle editor and writer of Insights and leads social media and direct marketing strategy. Kelley has worked at Mayo Clinic since 2013. Outside of work, you can find Kelley running, traveling, playing with her kitty, and exploring new foods.