The Research Roundup provides an overview of the past week’s research from Mayo Medical Laboratories consultants, including featured abstracts and complete list of published studies and reviews.
Nephron-sparing surgery is the preferred surgical management of cT1 renal masses, but observational and randomized data conflict regarding a survival benefit. Mayo Clinic researchers conducted a study to examine the associations of radical nephrectomy versus partial nephrectomy with oncologic and nononcologic outcomes. A total of 2459 adults were treated with radical nephrectomy or partial nephrectomy between 1990 and 2011 for a unilateral, sporadic, cT1, M0 solid renal mass. The study results found that although radical nephrectomy was associated with an increased risk of chronic kidney disease compared with partial nephrectomy, it was not associated with a statistically significant difference in cancer-specific mortality or all-cause mortality among patients with cT1 renal cell carcinoma. The study was published in European Urology.