Mayo Clinic Laboratory and Pathology Research Roundup: April 15
The Research Roundup provides an overview of the past week’s research from Mayo Clinic Laboratories consultants, including featured abstracts and a complete list of published studies and reviews.
Featured Abstract
Molecular Approach to Diagnosis of Cardiovascular Implantable Electronic Device Infection

Sonicate fluid (SF), a solution derived from vortexing and sonication of explanted cardiovascular implantable electronic devices (CIED), is a higher-yield specimen compared to swabs or tissues for culture-based detection of microorganisms associated with CIED infection. Despite this, SF culture fails to identify a causative organism in ~50% of cases. We aimed to evaluate the diagnostic performance of 16S ribosomal RNA gene (rRNA) PCR/sequencing of SF and compare it to that of SF culture.
Published to PubMed This Week
- Spermatic Cord Liposarcoma
Mayo Clinic Proceedings - Paraneoplastic Cast Nephropathy Associated with Pancreatic Mixed Acinar-Neuroendocrine Carcinoma: A Case Report
American Journal of Kidney Disorders - Heavy Chain Fibrillary Glomerulonephritis: A Case Report
American Journal of Kidney Disorders - Using Computer Assisted Morphometrics of 5-Year Biopsies to Identify Biomarkers of Late Renal Allograft Loss
American Journal of Transplant - Body Mass Index, Mammographic Density, and Breast Cancer Risk by Estrogen Receptor Subtype
Breast Cancer Research - Cardiac Magnetic Resonance in Patients with Elevated Troponin and Normal Coronary Angiography
Heart - Carboxyl Ester Lipase May Not Mediate Lipotoxic Injury during Severe Acute Pancreatitis
American Journal of Pathology - Suboptimal Response Rates to Hypomethylating Agent Therapy in Chronic Myelomonocytic Leukemia; a Single Institutional Study of 121 Patient
American Journal of Hematology - Prognostic Value of Minimal Residual Disease and Polyclonal Plasma Cells in Myeloma Patients Achieving a Complete Response to Therapy
American Journal of Hematology - Adrenal Cortical Carcinoma Associated with Lynch Syndrome: A Case Report and Review of Literature
Journal of the Endocrine Society - Cold Storage of Porcine Hepatocyte Spheroids for Spheroid Bioartificial Liver
Xenotransplantation - An Expanded Variant List and Assembly Annotation Identifies Multiple Novel Coding and Noncoding Genes for Prostate Cancer Risk Using a Normal Prostate Tissue eQTL Data Set
PLoS One - A Comparison of Adult Rhabdomyosarcoma and High Grade Neuroendocrine Carcinoma of the Urinary Bladder Reveals Novel PPP1R12A Fusions in Rhabdomyosarcoma
Human Pathology - Oncocytoma Presenting as a Fat-Containing Intraparotid Mass
Ear, Nose, Throat Jornal