Mayo Clinic Laboratory and Pathology Research Roundup: May 6

The Research Roundup provides an overview of the past week’s research from Mayo Clinic Laboratories consultants, including featured abstracts and a complete list of published studies and reviews.

Featured Abstract

Cytogenetic Clonal Evolution in Myeloproliferative Neoplasms: Contexts and Prognostic Impact Among 648 Patients with Serial Bone Marrow Biopsies

Karyotype is diagnostically and prognostically essential in patients with myeloproliferative neoplasms (MPN); cytogenetic abnormalities occur in approximately a third of patients with primary myelofibrosis (PMF) and 520% of those with essential thrombocythemia (ET) or polycythemia vera (PV). “Abnormal” karyotype in PV and “unfavorable” or “very high risk (VHR)” karyotype in
PMF have been associated with inferior survival.

Published to PubMed This Week

Alyssa Frank

Alyssa Frank is a Marketing Segment Manager at Mayo Clinic Laboratories. She leads marketing strategies for product management and specialty testing. Alyssa has worked at Mayo Clinic since 2015.