Mayo Clinic Laboratory and Pathology Research Roundup: May 13

By Alyssa Frank • May 13, 2019

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The Research Roundup provides an overview of the past week’s research from Mayo Clinic Laboratories consultants, including featured abstracts and a complete list of published studies and reviews.

Featured Abstract

Oncologic Outcomes Following Partial Nephrectomy and Percutaneous Ablation for cT1 Renal Masses

With mature follow-up at a single institution, percutaneous ablation appears to have acceptable results for cT1 renal tumors and is appropriate for patients with a contraindication for surgery. For cT1a patients, clinically relevant differences between partial nephrectomy and ablation are unlikely, and treatment choice should involve shared decision making. For cT1b patients, death from renal cell carcinoma was more common with cryoablation, and large differences in this outcome cannot be ruled out. Further research is needed to confirm the oncologic effectiveness of cryoablation in the cT1b setting

Published to PubMed This Week

• Small Intestinal Microbial Dysbiosis Underlies Symptoms Associated with Functional Gastrointestinal Disorders
  Nature Communication
• Splenic Hemangioma
  Mayo Clinic Proceedings
• A Systematic Review on Predisposition to Lymphoid (B and T cell) Neoplasias in Patients with Primary Immunodeficiencies and Immune Dysregulatory Disorders (Inborn Errors of Immunity)
  Frontiers in Immunology
• Sarcopenia and Response to Neoadjuvant Chemotherapy for Muscle-Invasive Bladder Cancer
  Clinical Genitourinary Cancer
• Relationship Between Free Hemoglobin (Hemolysis), Potassium and Ionized Calcium in Lithium Heparin Blood Gas Samples Collected Intraoperatively
  Clinical Biochemistry
• Subependymoma Involving Multiple Spinal Cord Levels: A Clinicopathological Case Series with Chromosomal Microarray Analysis
  Neuropathology
• RNA-Seq Detects a SAMD12-EXT1 Fusion Transcript and Leads to the Discovery of an EXT1 Deletion in a Child with Multiple Osteochondromas
  Molecular Genetics and Genomic Medicine
• Metabolomics in Stem Cell Biology Research
  Methods in Molecular Biology
  

Alyssa Frank

Alyssa Frank is a Marketing Segment Manager at Mayo Clinic Laboratories. She leads marketing strategies for product management and specialty testing. Alyssa has worked at Mayo Clinic since 2015.