Mayo Clinic Laboratory and Pathology Research Roundup: August 12

The research roundup provides an overview of the past week’s research from Mayo Clinic Laboratories consultants, including featured abstracts and a complete list of published studies and reviews.

Featured Abstract

Cohort Profile: The Right Drug, Right Dose, Right Time: Using Genomic Data to Individualize Treatment Protocol (RIGHT Protocol).

Genetic modulation of drug response can cause life-threatening adverse drug reactions, increase susceptibility to drug interactions and alter therapeutic effectiveness. Pharmacogenomics has the potential to immediately impact the care of patients and is a hallmark of genomic medicine worldwide. Ideally, pharmacogenomics-guided drug selection will produce optimal effects for specific indications, reduce delays in care to effective therapies, improve patient safety and reduce health care costs. Over the past decade, a large number of pharmacogenomic variants with demonstrated clinical utility have been identified and corresponding international guidelines for clinical implementation have been developed and published by the Clinical Pharmacogenetics Implementation Consortium (CPIC), Canadian Pharmacogenomics Network for Drug Safety (CPNDS) and Royal Dutch Association for the Advancement of Pharmacy Dutch Pharmacogenetics Working Group (DPWG). There is now general agreement that pharmacogenomics represents an area within genomic science that could have a significant positive impact on clinical medicine and, ultimately, affect every patient. Via The International Journal of Epidemiology.

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Published to PubMed This Week

Samantha Rossi

Samantha Rossi is a Digital Marketing Manager at Mayo Clinic Laboratories. She supports marketing strategies for product management and specialty testing. Samantha has worked at Mayo Clinic since 2019.