Mayo Clinic laboratory and pathology research roundup: January 18

By Samantha Rossi • January 18, 2021

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The research roundup provides an overview of the past week’s research from Mayo Clinic Laboratories consultants, including featured abstracts and a complete list of published studies and reviews.

Featured Abstract

CD10 (Neprilysin) Expression: A Potential Adjunct in the Distinction of Hibernoma from Morphologic Mimics.

Although the morphologic diagnosis of hibernoma is usually straightforward, some hibernomas have atypical morphologic features, mimicking atypical lipomatous tumor/well-differentiated liposarcoma (ALT/WDL). Additionally, the multivacuolated brown fat cells may be mistaken for lipoblasts by pathologists, especially those without significant soft tissue tumor exposure. Via Human Pathology

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Published to PubMed This Week

• Acetyl-CoA Synthetase 2: A Critical Linkage in Obesity-Induced Tumorigenesis in Myeloma.
  Cell Metabolism
• An integrated multi-omics approach to identify regulatory mechanisms in cancer metastatic processes.
  Genome Biology
• Precision Radiotherapy: Reduction in Radiation for Oropharyngeal Cancer in the 30 ROC Trial.
  Journal of the National Cancer Institution
• Integrated Molecular Characterization of Fumarate Hydratase-deficient Renal Cell Carcinoma.
  Clinical Cancer Research
• Management of acute kidney injury in symptomatic multiple myeloma.
  Kidney International
• Teaching NeuroImages: Linear radial periventricular enhancement in Glial Fibrillary Acidic Protein astrocytopathy.
  Neurology
• Paroxysmal Dysarthria-Ataxia in Multiple Sclerosis.
  Neurology
• Sex-Specific 99th Percentile URLs for Cardiac Troponin Assays-Their Time Has Come.
  Clinical Chemistry
• Clinical characteristics and outcomes of primary versus secondary gastrointestinal mantle cell lymphoma.
  Blood Cancer Journal
• In Reply - Micro-Thrombosis, Perfusion Defects, and Worsening Oxygenation in COVID-19 Patients: A Word of Caution on the Use of Convalescent Plasma.
  Mayo Clinic Proceedings

Samantha Rossi

Samantha Rossi is a Digital Marketing Manager at Mayo Clinic Laboratories. She supports marketing strategies for product management and specialty testing. Samantha has worked at Mayo Clinic since 2019.