Mayo Clinic laboratory and pathology research roundup: February 8

By Samantha Rossi • February 8, 2021

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The research roundup provides an overview of the past week’s research from Mayo Clinic Laboratories consultants, including featured abstracts and a complete list of published studies and reviews.

Featured Abstract

AGA clinical practice update on the management of refractory helicobacter pylori infection: Expert review.

The purpose of this CPU Expert Review is to provide clinicians with guidance on the management of H. pylori after an initial attempt at eradication therapy fails, including best practice advice on specific regimen selection, and consideration of patient and systems factors that contribute to treatment efficacy. This Expert Review is not a formal systematic review, but is based upon a review of the literature to provide practical advice. No formal rating of the strength or quality of the evidence was carried out. Accordingly, a combination of available evidence and consensus-based expert opinion were used to develop these best practice advice statements. Via Gastroenterology.

Read more.

Published to PubMed This Week

• Salicylates enhance CRM1 inhibitor antitumor activity by induction of S-phase arrest and impairment of DNA-damage repair.
  Blood
• Natural History of Monoclonal B-cell Lymphocytosis (MBL) Among Relatives in Chronic Lymphocytic Leukemia (CLL) Families.
  Blood
• Renal Neoplasia in Tuberous Sclerosis: A Study of 41 Patients.
  Mayo Clinic Proceedings
• Mev-stealth: A cd46-specific oncolytic measles virus resistant to neutralization by measles-immune human serum.
  PLoS Pathology
• Young platelet millionaires with essential thrombocythemia.
  American Journal of Hematology
• Acute myeloid leukemia after age 70 years: a retrospective comparison of survival following treatment with intensive vs HMA ± venetoclax chemotherapy.
  American Journal of Hematology
• Assessment of RAS Dependency for BRAF Alterations Using Cancer Genomic Databases.
  JAMA Network Open
• PLEKHA7, an Apical Adherens Junction Protein, Suppresses Inflammatory Breast Cancer in the Context of High E-Cadherin and p120-Catenin Expression.
  International Journal of Molecular Science
• Resurrecting the Hospital Autopsy: Impact of an Office of Decedent Affairs on Consent Rates, Providers, and Next-of-Kin.
  Archives of Pathology and Laboratory Medicine
• Analysis of Esophagectomy Margin Practice and Survival Implications.
  Annals of Thoracic Surgery

Samantha Rossi

Samantha Rossi is a Digital Marketing Manager at Mayo Clinic Laboratories. She supports marketing strategies for product management and specialty testing. Samantha has worked at Mayo Clinic since 2019.