Mayo Clinic laboratory and pathology research roundup: June 22

By Samantha Rossi • June 22, 2021

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The research roundup provides an overview of the past week’s research from Mayo Clinic Laboratories consultants, including featured abstracts and a complete list of published studies and reviews.

Featured Abstract

Acute treatments for episodic migraine in adults: A systematic review and meta-analysis. 

Independent reviewers selected studies and extracted data. Meta-analysis was performed with the DerSimonian-Laird random-effects model with Hartung-Knapp-Sidik-Jonkman variance correction or by using a fixed-effect model based on the Mantel-Haenszel method if the number of studies was small. Via JAMA

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Published to PubMed This Week

• A molecular pathology, neurobiology, biochemical, genetic and neuroimaging study of progressive apraxia of speech. 
  Nature Communications
• RAS mutations drive proliferative chronic myelomonocytic leukemia via a KMT2A-PLK1 axis. 
  Nature Communications
• Characteristics and spatially-defined immune (micro)landscapes of early-stage PD-L1-positive triple-negative breast cancer. 
  Clinical Cancer Research
• Teaching neuroImages: Linear radial periventricular enhancement in glial fibrillary acidic protein astrocytopathy. 
  Neurology
• Identification of genetic causes of focal segmental glomerulosclerosis increases with proper patient selection. 
  Mayo Clinic Proceedings
• Microbiology of hip and knee periprosthetic joint infections: A database study. 
  Clinical Microbiology and Infections
• Blocking the TSH receptor with K1-70™ in a patient with follicular thyroid cancer, Graves' disease and Graves' ophthalmopathy. 
  Thyroid
• Venetoclax for the treatment of multiple myeloma: Outcomes outside of clinical trials. 
  American Journal of Hematology
• Evaluation of self-collected mid-turbinate nasal swabs and saliva for detection of SARS-CoV-2 RNA. 
  Journal of Clinical Microbiology
• The combination of venetoclax and Ixazomib selectively and efficiently kills HIV-Infected cell lines but has unacceptable toxicity in primary cell models. 
  Journal of Virology

Samantha Rossi

Samantha Rossi is a Digital Marketing Manager at Mayo Clinic Laboratories. She supports marketing strategies for product management and specialty testing. Samantha has worked at Mayo Clinic since 2019.