Mayo Clinic Laboratory and pathology research roundup: October 19

By Chantell Canfield • October 19, 2021

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The research roundup provides an overview of the past week’s research from Mayo Clinic Laboratories consultants, including featured abstracts and a complete list of published studies and reviews.

Featured Abstract

Autopsy validation of progressive supranuclear palsy-predominant speech/language disorder criteria.

 Progressive supranuclear palsy (PSP) may present as a speech/language disorder (PSP-SL). Thirty-four prospectively recruited patient with s.o. PSP-SL completed comprehensive speech/language and neurological assessments longitudinally, died, and underwent autopsy. Via PubMed

Read more.

Published to PubMed This Week

• High-oxygen-affinity hemoglobinopathy-associated erythrocytosis: clinical outcomes and impact of therapy in 41 cases.
  American Journal of Hemotology
• Neurofascin-155 immunoglobulin subtypes: Clinicopathologic associations and neurologic outcomes.
  Neurology
• Autoimmune encephalitis post-SARS-CoV-2 infection: Case frequency, findings, and outcomes.
  Neurology
• Diagnostic value of 16S ribosomal RNA gene polymerase chain reaction/sanger sequencing in clinical practice.
  Clinical Infectious Diseases
• T2* reduction in patients with acute post-traumatic headache.
  Cephalalgia
• Quinacrine has preferential anticancer effects on mesothelioma cells with inactivating NF2 mutations.
  Frontiers in Pharmacology
• Outcomes of epilepsy surgery in the older population: not too old, not too late.
  Journal of Neurosurgery
• COVID-19 vaccination and glomerulonephritis.
  Kidney International Reports
• Amplification of femtograms of bacterial DNA within 3 h using a digital microfluidics platform for MinION sequencing.
  ACS Omega
• Genetic features and clinical outcomes of patients with isolated and comutated DDX41-mutated myeloid neoplasms.
  Blood Advances

Chantell Canfield

Chantell Canfield is a web content coordinator for Mayo Clinic Laboratories. She began working for Mayo Clinic in 2021.