Mayo Clinic Laboratory and pathology research roundup: February 15

By Chantell Canfield • February 15, 2022

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The research roundup provides an overview of the past week’s research from Mayo Clinic Laboratories consultants, including featured abstracts and a complete list of published studies and reviews.

Featured Abstract

Atrial shunt device for heart failure with preserved and mildly reduced ejection fraction (REDUCE LAP-HF II): a randomised, multicentre, blinded, sham-controlled trial.

Placement of an interatrial shunt device reduces pulmonary capillary wedge pressure during exercise in patients with heart failure and preserved or mildly reduced ejection fraction. We aimed to investigate whether an interatrial shunt can reduce heart failure events or improve health status in these patients.

Read more.

Published to PubMed This Week

• How to embrace gene therapy in Gastroenterology.
  Gastroenerology
• Introduction to 2021 WHO classification of thoracic tumors.
  Journal of Thoracic Oncology
• Genetic polymorphisms and correlation with treatment induced cardiotoxicity and prognosis in breast cancer patients.
  Clinical Cancer Research
• Measles, rubella, and mumps titers post chemotherapy plus autologous stem cell transplant in multiple myeloma patients.
  American Journal of Hematology
• Deciphering the individual contribution of absolute neutrophil and monocyte counts to thrombosis risk in polycythemia vera and essential thrombocythemia.
  American Journal of Hematology
• Effectiveness of BNT162b2 and mRNA-1273 Second Doses and Boosters for SARS-CoV-2 infection and SARS-CoV-2 Related Hospitalizations: A Statewide Report from the Minnesota Electronic Health Record Consortium.
  Clinical Infectious Diseases
• Kidney Transplantation in Patients With Monoclonal Gammopathy of Renal Significance (MGRS)-Associated Lesions: A Case Series.
  American Journal of Kidney Diseases
• White matter damage due to vascular, tau, and TDP-43 pathologies and its relevance to cognition.
  Acta Neuropathologica Communications
• Desmoid tumor and multiple colon adenomas.
  Mayo Clinic Proceedings
• Hemochromatosis.
  Mayo Clinic Proceedings

Chantell Canfield

Chantell Canfield is a web content coordinator for Mayo Clinic Laboratories. She began working for Mayo Clinic in 2021.