Mayo Clinic Laboratory and pathology research roundup: March 8

By Chantell Canfield • March 8, 2022

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The research roundup provides an overview of the past week’s research from Mayo Clinic Laboratories consultants, including featured abstracts and a complete list of published studies and reviews.

Featured Abstract

Androgen deprivation therapy use and duration with definitive radiotherapy for localized prostate cancer: an individual patient data meta-analysis.

Randomised trials have investigated various androgen deprivation therapy (ADT) intensification strategies in men receiving radiotherapy for the treatment of prostate cancer. This individual patient data meta-analysis of relevant randomised trials aimed to quantify the benefit of these interventions in aggregate and in clinically relevant subgroups.

Read more.

Published to PubMed This Week

• Asxl1 loss cooperates with oncogenic Nras in mice to reprogram the immune microenvironment and drive leukemic transformation.
  Blood
• IMPROvE-CED Trial: Intracoronary autologous CD34+ cell therapy for treatment of coronary endothelial dysfunction in patients with angina and nonobstructive coronary arteries.
  Circulation Research
• Thymic Carcinomas - A concise multidisciplinary update on recent developments from the thymic carcinoma working group of the international thymic malignancy interest group.
  Journal of Thorac Oncology
• Reprint of "Introduction to 2021 WHO classification of thoracic tumors".
  Journal of Thorac Oncology
• LGI1 antibody encephalitis: acute treatment comparisons and outcome.
  Journal of Neurology, Neurosurgery, and Psychiatry
• Lymphocytopenia predicts shortened survival in myelodysplastic syndrome with ring sideroblasts (MDS-RS) but not in MDS/MPN-RS-T.
  American Journal of Hematology
• Outcomes for ESD of pathologically staged T1b esophageal cancer: A multi-center study.
  Gastrointestinal Endoscopy
• Comparative study of therapy-related and de novo adult b-cell acute lymphoblastic leukaemia.
  British Journal of Haemotology
• Cladribine therapy for advanced and indolent systemic mastocytosis: Mayo Clinic experience in 42 consecutive cases.
  British Journal of Haemotology
• Particle therapy for breast cancer.
  Cancers

Chantell Canfield

Chantell Canfield is a web content coordinator for Mayo Clinic Laboratories. She began working for Mayo Clinic in 2021.