Small Fiber Neuropathy: Diagnosis and Treatment

Specialty Webinar

Expires: April 13, 2024


The complex field of neuropathy can be challenging for any neurologist, but add on to that the recent discoveries related to small-fiber neuropathy and the growing incidence of autoimmune etiology and it can quickly become overwhelming. This “Specialty Testing” webinar will discuss the considerations physicians must weigh when evaluating suspected neuropathy patients, with special emphasis on small-fiber neuropathy and the most appropriate laboratory testing related to that phenotype. Understanding the clinical features and being able to identify the potential comorbidities associated with this rare but increasing disease can prevent delays in diagnosis. Furthermore, understanding the diagnostic potential and limitations of associated laboratory testing will assist clinicians with test interpretation.


Video length: 50 minute


Christopher Klein, M.D.

Christopher Klein, M.D.

Professor of Neurology
Mayo Clinic College of Medicine and Science
Department of Neurology
Mayo Clinic, Rochester, Minnesota

Learning objectives

Upon completion of this activity, participants should be able to:

  • Discuss recent discoveries related to SFN incidence, prevalence, comorbid conditions, longitudinal impairments and disabilities.
  • Identify appropriate laboratory testing to guide therapies.
  • Discuss role of autoantibody testing and highlight phenotype-specific approach.

Intended audience

This webinar is designed for any provider who sees patients with neurologic diseases (e.g., neurologists, psychiatrists, and primary care physicians, including internists and family care practitioners) as well as pathologists, laboratory directors, and laboratory send-out coordinators.


The following types of credit are offered for this event:


Mayo Clinic Laboratories is approved as a provider of continuing education programs in the Clinical Laboratory Sciences by the ASCLS P.A.C.E.® program. This program has been approved for a maximum of 1.0 P.A.C.E.® contact hour.

State of California

Mayo Clinic Laboratories is approved as a Continuing Education Accrediting Agency for Clinical Laboratory Sciences for the State of California. This program has been approved for 1.0 contact hour.

State of Florida

Mayo Clinic Laboratories is approved as a Continuing Education Accrediting Agency for the Clinical Laboratory Sciences for the State of Florida. Florida Board of Clinical Laboratory Personnel has designated this program for General credit. This program has been approved for 1.0 contact hour.

To obtain credit

1. Watch the video.

2. Complete the posttest and evaluation that launches immediately following the video.

3. Generate and print your certificate(s).

Level of instruction for this program is intermediate.

Faculty disclosure

Course director(s), planning committee, faculty, and all others who are in a position to control the content of this educational activity are required to disclose all relevant financial relationships with any commercial interest related to the subject matter of the educational activity. Safeguards against commercial bias have been put in place. Faculty members also will disclose any off-label and/or investigational use of pharmaceuticals or instruments discussed in their presentations. Disclosure of this information will be published in course materials so those participants in the activity may formulate their own judgments regarding the presentations.

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MCL Education (@mmledu)

MCL Education

This post was developed by our Education and Technical Publications Team.