Mayo Clinic Laboratory and pathology research roundup: May 17

By Meghann Southwick • May 17, 2022

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The research roundup provides an overview of the past week’s research from Mayo Clinic Laboratories consultants, including featured abstracts and a complete list of published studies and reviews.

Featured Abstract

Rapid exclusion of acute myocardial injury and infarction with a single high sensitivity cardiac troponin T in the emergency department: A multicenter United States evaluation.

There are good data to support using a single high-sensitivity cardiac troponin T (hs-cTnT) below the limit of detection (LoD) of 5 ng/L to exclude acute myocardial infarction.  total of 85,610 patients were evaluated in the CV Data Mart Biomarker cohort, amongst which 24,646 (29%) had a baseline hs-cTnT<6 ng/L. Women were more likely than men to have hs-cTnT<6 ng/L (38% vs. 20%, p<0.0001).

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Published to PubMed This Week

• Letter to the editor regarding "Fifth generation cellular networks and neurosurgery: A narrative review".
  World neurosurgery
• Lacrimal gland involvement in a patient with sarcoidosis.
  Cleveland Clinic journal of medicine
• Predictors and long-term impact of de novo aortic regurgitation in continuous flow left ventricular assist devices using vena contracta.
  ASAIO journal
• Senior authorship in academic radiology journals: Roles, responsibilities, and rewards.
  Academic radiology
• P38 initiates degeneration of midbrain GABAergic and glutamatergic neurons in diabetes models.
  The European journal of neuroscience
• The COX-2-PGE2 pathway promotes tumor evasion in colorectal adenomas.
  Cancer prevention research
• Substance use screening in transplant populations: recommendations from a consensus workgroup.
  Transplantation reviews
• Correction: A SISCAPA-based approach for detection of SARS-CoV-2 viral antigens from clinical samples.
  Clinical proteomics
• Association between baseline body mass index and survival in men with metastatic hormone-sensitive prostate cancer: ECOG-ACRIN CHAARTED E3805.
  The Prostate
• Beyond GWAS of colorectal cancer: Evidence of interaction with alcohol consumption and putative causal variant for the 10q24.2 region.
  Cancer epidemiology, biomarkers, & prevention

Meghann Southwick

Meghann Southwick is a marketing specialist for Mayo Clinic Laboratories. She has worked at Mayo Clinic since 2021.