Transfusion Safety in 2022: Experienced Phlebotomists and Electronic Systems are Key

Expiration date: May 18, 2024

Video length: 59:00


Every blood banker’s nightmare is the occurrence of an acute hemolytic transfusion reaction, and we spend a great deal of time and energy trying to avoid them. All our lab work has created a greater margin of safety and these events are rare. However, the key to success is getting the right person’s blood into the correctly labeled tube, which is the crucial job of the phlebotomist.

This "Phlebotomy Webinar" will provide basic information on blood compatibility, the consequences of incompatibility, and the recognition of an acute hemolytic transfusion reaction. Strategies to ensure that the right patient’s blood is collected will be discussed. Potential interventions will be outlined and then assessed in terms of their strength in error prevention. Consideration of prevention strength can be a good tool to find the best prevention solution.


Paula Santrach, M.D.

Consultant, Transfusion Medicine
Department of Laboratory Medicine and Pathology
Mayo Clinic, Rochester, Minnesota

Learning objectives

Upon completion of this activity, participants should be able to:

  • Recognize the signs, symptoms, and potential outcomes of acute hemolytic transfusion reactions (AHTR).
  • Identify the most common causes of an AHTR.
  • Identify interventions to reduce and/or prevent such reactions.
  • Assess the strength (likelihood of success) for potential interventions.

Intended audience

This series is appropriate for phlebotomists, phlebotomy managers, phlebotomy educators, and other patient care staff involved in specimen collection.


The following types of credit are offered for this event:


Mayo Clinic Laboratories is approved as a provider of continuing education programs in the Clinical Laboratory Sciences by the ASCLS P.A.C.E.® program. This program has been approved for a maximum of 1.0 P.A.C.E.® contact hour.

State of Florida

Mayo Clinic Laboratories is approved as a Continuing Education Accrediting Agency for the Clinical Laboratory Sciences for the State of Florida. Florida Board of Clinical Laboratory Personnel has designated this program for General credit. This program has been approved for 1.0 contact hour.

To obtain credit

1. Watch the video.

2. Complete the posttest and evaluation that launches immediately following the video.

3. Generate and print your certificate(s).

Level of instruction for this program is intermediate.

Faculty disclosure

Course director(s), planning committee, faculty, and all others who are in a position to control the content of this educational activity are required to disclose all relevant financial relationships with any commercial interest related to the subject matter of the educational activity. Safeguards against commercial bias have been put in place. Faculty members also will disclose any off-label and/or investigational use of pharmaceuticals or instruments discussed in their presentations. Disclosure of this information will be published in course materials so those participants in the activity may formulate their own judgments regarding the presentations.


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MCL Education

This post was developed by our Education and Technical Publications Team.