Mayo Clinic Laboratory and pathology research roundup: July 26

By Samantha Rossi • July 26, 2022

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The research roundup provides an overview of the past week’s research from Mayo Clinic Laboratories consultants, including featured abstracts and a complete list of published studies and reviews.

Featured Abstract

Motor-neuron-disease-like phenotype associated with IgLON5 disease.

A growing spectrum of neurological manifestations are being recognized in association with IgLON5 autoimmunity, including recent reports of motor-neuron-disease-like phenotype. Here we describe four cases of IgLON5 autoimmunity with motor neuron involvement and evaluate an additional 109 probable or definite amyotrophic lateral sclerosis cases seen in our neuromuscular clinic for IgLON5-IgG seropositivity.

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Published to PubMed This Week

• The clinical approach to diagnosing peri-procedural myocardial infarction after percutaneous coronary interventions according to the fourth universal definition of myocardial infarction - from the study group on biomarkers of the European Society of Cardiology (ESC) Association for Acute CardioVascular Care (ACVC).
  Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals
• Spurious CD34 expression in b-cell lymphoma due to nonspecific binding to PerCP-Cy5.5 fluorochrome conjugates: a rare phenomenon and a diagnostic pitfall.
  Cytometry. Part B, Clinical cytometry
• Pembrolizumab in combination with neoadjuvant chemoradiotherapy for patients with resectable adenocarcinoma of the gastroesophageal junction.
  Clinical cancer research : an official journal of the American Association for Cancer Research
• A systematic review supporting the endocrine society clinical practice guideline for the management of hyperglycemia in adults hospitalized for noncritical Illness or undergoing elective surgical procedures.
  The Journal of clinical endocrinology and metabolism
• Surveillance mammography in older breast cancer survivors: current practice patterns and patient perceptions.
  Journal of geriatric oncology
• Causes of death in low grade b-cell lymphomas in the rituximab era: a prospective cohort study.
  Blood advances
• Machine learning-based fragment selection improves the performance of qualitative PRM assays.
  Journal of proteome research
• Tissue methylated DNA markers for sporadic pancreatic cancer are strongly associated with familial and genetically predisposed pancreatic cancer.
  Pancreatology : official journal of the International Association of Pancreatology
• Neuropathologic scales of cerebrovascular disease associated with diffusion changes on MRI.
  Acta neuropathologica
  
  

Samantha Rossi

Samantha Rossi is a Digital Marketing Manager at Mayo Clinic Laboratories. She supports marketing strategies for product management and specialty testing. Samantha has worked at Mayo Clinic since 2019.