Mayo Clinic Laboratory and pathology research roundup: August 9

By Samantha Rossi • August 9, 2022

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The research roundup provides an overview of the past week’s research from Mayo Clinic Laboratories consultants, including featured abstracts and a complete list of published studies and reviews.

Featured Abstract

Type 1, Type 2 myocardial infarction and non-ischemic myocardial injury-opinion from the front lines

Differentiating patients with type 1 and type 2 myocardial infarction (MI) and acute non-ischemic myocardial injury continues to be a problem for many clinicians. Type 1 MI is the most easily defined. It involves the rise and fall of blood troponin measurements (only falling values if the patient arrives late) with an appropriate clinical observation consistent with myocardial ischemia. Diagnosis and therapy of type 1 MI are well understood and usually present no problem to the physician.

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Published to PubMed This Week

• Prognostic implications of a morphometric evaluation for chronic changes on all diagnostic native kidney biopsies
  Journal of the American Society of Nephrology
• High-resolution mass spectrometry for the measurement of PTH and PTH fragments: insights into PTH physiology and bioactivity
  Journal of the American Society of Nephrology
• A mentorship model for neurosurgical training: the Mayo Clinic experience
  Neurosurgical focus
• A knowledge-based discovery approach couples artificial neural networks with weight engineering to uncover immune-related processes underpinning clinical traits of breast cancer
   Frontiers in immunology
• Surgical pathology of diffuse parenchymal lung disease in patients with psoriasis or psoriatic arthritis
  Archives of pathology & laboratory medicine
• Making decisions about Krabbe disease newborn screening
  Pediatrics
• Cellular senescence: a key therapeutic target in aging and diseases
  The Journal of clinical investigation
• Color vision deficiency survey in anatomic pathology
  American journal of clinical pathology
• Population pharmacokinetics of Z-endoxifen in patients with advanced solid tumors
  Journal of clinical pharmacology
• Identification of dysbetalipoproteinemia by an enhanced Sampson-NIH equation for very low-density lipoprotein-cholesterol
  Frontiers in genetics
• A knowledge-based discovery approach couples artificial neural networks with weight engineering to uncover immune-related processes underpinning clinical traits of breast cancer
  Frontiers in immunology
• The publication impact of the first 100 THOR network publications by bibliometric and social network analyses
  Transfusion
• Clinical course and imaging characteristics of benign adrenal cysts: a single-center study of 92 patients
  European journal of endocrinology
• Malignant rhabdoid tumor: cyto-histologic correlation and immunohistochemical characterization of a rare pediatric malignancy and its differential diagnoses
  Annals of diagnostic pathology
• Course design and learning outcomes of a practical online ergonomics course for surgical residents
  Journal of surgical education
• Therapy-related myeloid neoplasms following chimeric antigen receptor T-cell therapy for Non-Hodgkin lymphoma
  Blood cancer journal
• Lumbar stenosis due to wild-type transthyretin amyloid-induced thickening of the ligamentum flavum: a separate etiology from degeneration of intervertebral discs?
  Journal of neurosurgery
• Comprehensive diabetes autoantibody laboratory-based clinical service testing in 6044 consecutive patients: analysis of age and sex effects
  The journal of applied laboratory medicine
• The need to develop clinical guidance for the use of high-sensitivity cardiac troponin in pediatric and neonatal patients
  Clinical chemistry
• Short- and long-term biological variability of small dense LDL, HDL3, and triglyceride-rich lipoprotein cholesterol
  The journal of applied laboratory medicine
• Analysis of somatic mutations in 131 human brains reveals aging-associated hypermutability
  Science
• Pemetrexed plus lenalidomide for relapsed/refractory primary central nervous system lymphoma: a prospective single-arm phase II study
  Frontiers in oncology
  
  

Samantha Rossi

Samantha Rossi is a Digital Marketing Manager at Mayo Clinic Laboratories. She supports marketing strategies for product management and specialty testing. Samantha has worked at Mayo Clinic since 2019.