Mayo Clinic Laboratory and pathology research roundup: September 12

By Samantha Rossi • September 12, 2023

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The research roundup provides an overview of the past week’s research from Mayo Clinic Laboratories consultants, including featured abstracts and a complete list of published studies and reviews.

Featured Abstract

Activated mast cells in periprosthetic joint infection-associated tissue.

Periprosthetic joint infection (PJI) is a devastating complication of total joint arthroplasty surgery. Increased densities of activated mast cells have been predicted to be present in PJI compared to non-infectious arthroplasty failure based on analysis of transcriptomic data, but their presence in PJI-associated periprosthetic tissues has not been visually confirmed.

Read more.

Published to PubMed This Week

• Teaching neuroimages: Pachymeningitis and aortitis as the initial presentation of granulomatosis with polyangiitis.
  Neurology
• Therapeutic efficacy of temsirolimus in a patient-derived model of metastatic fibrolamellar hepatocellular carcinoma.
  In Vivo
• A 20-year analysis of medicare reimbursement for abdominal wall reconstruction (2000 to 2020).
  Plastic Reconstructive Surgery
• Mucoepidermoid carcinoma.
  Mayo Clinic Proceedings
• Do early relapses predict the risk of long-term relapsing disease in an adult and paediatric cohort with MOGAD?
  Annals of Neurology
• In vitro activity of hypochlorous acid generating electrochemical bandage against monospecies and dual-species bacterial biofilms.
  Journal of Applied Microbiology
• A globally applicable "triple A" risk model for essential thrombocythemia based on Age, Absolute neutrophil count, and Absolute lymphocyte count.
  American Journal of Hematology
• Association of moyamoya vasculopathy with autoimmune disease: a systematic review and pooled analysis.
  Neurosurgical Review
• Tenascin-r autoimmunity: Isolated tremor reversed with immunotherapy.
  Annals of Neurology
• Superior detection rate of plasma cell FISH using FACS-FISH.
  American Journal of Clinical Pathology
• Gastrointestinal amyloidosis: An often unexpected finding with systemic implications.
  Human Pathology
• SMARCAL1: Expanding the spectrum of genes associated with alternative lengthening of telomeres.
  Neuro Oncology
• Prospective evaluation of genome sequencing to compare conventional cytogenetics in acute myeloid leukemia.
  Blood Cancer Journal

Samantha Rossi

Samantha Rossi is a Digital Marketing Manager at Mayo Clinic Laboratories. She supports marketing strategies for product management and specialty testing. Samantha has worked at Mayo Clinic since 2019.