Mayo Clinic Laboratory and Pathology Research Roundup: October 10

By Sarah Jarvis • October 10, 2023

Share this:

The research roundup provides an overview of the past week’s research from Mayo Clinic Laboratories consultants, including featured abstracts and a complete list of published studies and reviews.

Featured Abstract

Mayo Clinic consensus report on membranous nephropathy: proposal for a novel classification.

Membranous nephropathy (MN) is a pattern of injury caused by autoantibodies binding to specific target antigens, with accumulation of immune complexes along the subepithelial region of glomerular basement membranes. The past 20 years have brought revolutionary advances in the understanding of MN, particularly via the discovery of novel target antigens and their respective autoantibodies. These discoveries have challenged the traditional classification of MN into primary and secondary forms. 

Read more.

Published to PubMed This Week

• Atypical presentation of a rare disorder; idiopathic myointimal hyperplasia of mesenteric veins (IMHMV): Report of two cases.
  International Journal of Surgery Case Reports
• Recurrent atypical anti-glomerular basement membrane nephritis in the kidney transplant.
  American Journal of Transplantation
• Granularity in disease classification impacts survival prediction in advanced systemic mastocytosis: A single institution study of 329 informative cases.
  American Journal of Hematology
• Germline mutations in 12 genes and risk of ovarian cancer in three population-based cohorts.
  Cancer Epidemiology, Biomarkers & Prevention
• Feasibility of probe washing after stereotactic needle biopsy as a novel technique for developing cell lines and xenografts of H3 K27-altered diffuse midline gliomas.
  Journal of Neurosurgery
• Vertical transmission of SARS-CoV-2-specific antibodies and cytokine profiles in pregnancy.
  The Journal of Infectious Diseases
• Identification of SKOR2 IgG as a novel biomarker of paraneoplastic neurologic syndrome.
  Frontiers of Immunology
• Confirmation of insertion, deletion, and deletion-insertion variants detected by next-generation sequencing.
  Clinical Chemistry
• PAX8-positive (gynecologic-type) clear cell carcinoma metastatic to the kidney.
  Mayo Clinic Proceedings
• Genomic analysis of spermatocytic tumors demonstrates recurrent molecular alterations in cases with malignant clinical behavior.
  The Journal of Pathology
• Update on endoscopic dysplasia surveillance in inflammatory bowel disease.
  The American Journal of Gastroenterology
• The immunome of mobilized peripheral blood stem cells is predictive of long-term outcomes and therapy-related myeloid neoplasms in patients with multiple myeloma undergoing autologous stem cell transplant.
  Blood Cancer Journal

Sarah Jarvis

Sarah Jarvis is a Senior Marketing Specialist at Mayo Clinic Laboratories. She supports marketing strategies for paid media.