Mayo Clinic Laboratory and Pathology Research Roundup: January 23

By Sarah Jarvis • January 23, 2024

Share this:

The research roundup provides an overview of the past week’s research from Mayo Clinic Laboratories consultants, including featured abstracts and a complete list of published studies and reviews.

Featured Abstract

Carcinoembryonic antigen-expressing oncolytic measles virus derivative in recurrent glioblastoma: a phase 1 trial.

Measles virus (MV) vaccine strains have shown significant preclinical antitumor activity against glioblastoma (GBM), the most lethal glioma histology. In this first in human trial (NCT00390299), a carcinoembryonic antigen-expressing oncolytic measles virus derivative (MV-CEA), was administered in recurrent GBM patients either at the resection cavity (Group A), or, intratumorally on day 1, followed by a second dose administered in the resection cavity after tumor resection on day 5 (Group B). 

Read more.

Published to PubMed This Week

• Venetoclax plus hypomethylating agents in DDX41-mutated acute myeloid leukaemia and myelodysplastic syndrome: Mayo Clinic series on 12 patients.
  British Journal of Haemotology
• The lymphoma epidemiology of outcomes cohort study: Design, baseline characteristics, and early outcomes.
  American Journal of Hematology
• HOCl-producing electrochemical bandage for treating pseudomonas aeruginosa-infected murine wounds.
  Antimicrobial Agents and Chemotherapy
• Temporal trends in antifungal susceptibility of cryptococcus neoformans isolates from a reference laboratory in the United States, 2011-2021.
  Mycoses
• Analysis of vitamin D₃-sulfate and 25-hydroxyvitamin D₃-sulfate in breastmilk by LC-MS/MS.
  Journal of Chromatography
• Cold platelet transfusion: The effects of a fluid warmer on platelet function.
  Transfusion
• Characteristics of normal weight Insulin-resistant adults with unfavorable health outcomes.
  Metabolic Syndrome and Related Disorders
• Detection of histoplasma capsulatum and blastomyces dermatitidis antigens in serum using a single quantitative enzyme immunoassay.
  Journal of Clinical Microbiology
• Lophomonas as a respiratory pathogen-jumping the gun.
  Journal of Clinical Microbiology
• Circulating immunophenotypes are potentially prognostic in follicular cell-derived thyroid cancer.
  Frontiers of Immunology
• Peripheral nervous system manifestations of MOG antibody associated disease.
  Annals of Clinical and Translational Neurology
• Extent of surgical resection as a predictor of tumor progression in skull base chordomas: A multicenter volumetric analysis.
  World Neurosurgery

Sarah Jarvis

Sarah Jarvis is a Senior Marketing Specialist at Mayo Clinic Laboratories. She supports marketing strategies for paid media.