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A simpler path to answers for patients with mast cell activation syndrome

A random urine test panel aids in diagnosing mast cell activation syndrome (MCAS), a complex condition often misdiagnosed due to overlapping symptoms. The panel improves access, speeds up diagnosis, and enables individualized treatment by detecting key mast cell mediators.

August 11, 2025
Rabbits, Chikungunya, and More Viral News: Matthew Binnicker, Ph.D.
August 28, 2025

In this episode of “Answers From the Lab,” host Bobbi Pritt, M.D., chair of the Division of Clinical Microbiology at Mayo Clinic, and Matthew Binnicker, Ph.D., a microbiologist and virologist and chief scientific officer of Mayo Clinic Laboratories, discuss recent developments in viral infections.

Elevating Clinical Lab Websites in a Changing Technology Landscape
August 25, 2025

In this episode of the “Leveraging the Laboratory” podcast, host Jane Hermansen, outreach manager at Mayo Clinic Laboratories, is joined by Travis Engelhaupt, digital experience director, and Naomi Lovell, project manager. Together, they discuss website trends and best practices.

Practical Legal Insight and Tips: Compliance Issues for Hospital Laboratory Outreach Programs
August 20, 2025

Register now – Nov. 19, 2025: Regulatory compliance and recent policy changes at the federal and state levels relevant to hospital laboratory outreach programs.

BCR/ABL1 Testing [Test in Focus]
July 16, 2019

David Viswanatha, M.D., a hematopathologist and co-director of the molecular hematology and complete genome sequencing laboratories at Mayo Clinic, provides an overview of BCR/ABL1 testing, discusses the best testing methods, NCCN/ELN criteria guidelines, why FISH testing is no longer routinely available at Mayo Clinic, and what test to order at what time for CML patients.

CMS Date of Service Policy
July 1, 2019

If your organization refers outpatient testing to Mayo Clinic Laboratories (MCL) for molecular pathology tests, the performing laboratory will be required to bill Medicare directly for tests that meet specific requirements. This new exception to the laboratory Date of Service (DOS) policy will not apply to advanced laboratory diagnostic tests (ADLTs) or molecular pathology tests performed on a specimen collected from a hospital inpatient.

Communiqué
GFAP: Novel Test for a Newly Identified Meningoencephalomyelitis
June 28, 2019

Mayo Clinic Laboratories is the only laboratory in the world to offer testing for a novel form of autoimmune meningoencephalomyelitis. Known as autoimmune glial fibrillary acidic protein (GFAP) astrocytopathy, the condition was identified by Mayo Clinic in 2016. The GFAP antibody test is offered as part of Mayo Clinic Laboratories’ encephalitis and myelopathy evaluations.

CPT Codes and LOINC Update: May 2019
June 27, 2019

View a full list of new CPT codes, Test Classification Updates, LOINC Codes, and Z-Codes posted to mayocliniclabs.com during the month of May 2019.

Mayo Clinic Laboratory and Pathology Research Roundup: June 24
June 24, 2019

This week's research roundup features a study on RINT1 bi-allelic variations that cause infantile-onset recurrent acute liver failure and skeletal abnormalities.

Mayo Clinic Laboratory and Pathology Research Roundup: June 17
June 17, 2019

This week's research roundup features a study on late relapses in patient with diffuse large b-cell lymphoma who were treated with immunochemotherapy.

Gastrointestinal Stromal Tumor Panel [Test in Focus]
June 12, 2019

Rondell P. Graham, M.B.B.S., gives an overview of this test available through Mayo Clinic Laboratories. He discusses when this testing should be ordered, how this testing improves upon previous testing approaches, what clinical action can be taken due to the results of this testing.

Autoimmune Myelopathy Evaluation [Test in Focus]
June 12, 2019

Patients with autoimmune myelopathy present with subacute onset and rapid progression of spinal cord symptoms (weakness, gait difficulties, loss of sensation, neuropathic pain, and bowel and bladder dysfunction). Autoimmune myelopathy evaluation of serum and spinal fluid can assist in the diagnosis and aid distinction from other causes of myelopathy (multiple sclerosis, sarcoidosis, and vascular disease). Early diagnosis may assist in diagnosis of occult cancer, prompt initiation of immune therapies, or both.

Mayo Clinic Laboratory and Pathology Research Roundup: June 10
June 10, 2019

This week's research roundup features research on the phase II evaluation of aggressive dose de-escalation for adjuvant chemoradiotherapy in human pappillomavirus-associated oropharynx squamous cell carcinoma.

Curtis Hanson, M.D., Discusses Prognostic Markers for Chronic Lymphocytic Leukemia
June 6, 2019

Curtis Hanson, M.D., discusses the importance of detecting immunoglobulin heavy-chain variable region gene (IGHV) when acquiring prognostic and potentially therapeutic information in chronic lymphocytic leukemia (CLL) patients in CAP TODAY.

New Tests Launched in May
June 5, 2019

In May 2019, Mayo Clinic Laboratories announced four new tests along with numerous reference value changes, obsolete tests, and algorithm changes.

Communiqué
Cutting-Edge Bacterial Testing for the Diagnosis of Patient Infections and Outbreak Mitigation
June 4, 2019

Mayo Clinic Laboratories is one of the few laboratories in the country to offer two special sequencing-based tests for bacteria in its catalog. The first test is designed to help protect patients by investigating potential outbreaks of a single bacterial species or by identifying recurrent infections in an individual patient. The second has the ability to detect DNA of any bacteria to help identify the cause of an infection.

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