Cardiovascular pathology

A multidisciplinary approach to care

The section of cardiovascular pathology handles a wide variety of specimens from the heart and the body's vasculature. We practice a multidisciplinary approach to the consultative practice, leveraging our radiology and cardiology colleagues to review challenging cases and to arrive at an efficient and specific diagnosis that is clinically actionable. Our patient-centric mission is at the heart of our approach.

Mayo Clinic Laboratories is the only lab in the United States that performs proteomic typing by tandem mass spectrometry on blood, dried blood spot, and formalin-fixed, paraffin-embedded tissue specimens. Genetic testing for cardiomyopathies, hereditary arrhythmia syndromes, and aortopathies may be added to pathology consultations as indicated or performed as stand-alone testing at the request of the ordering provider.

3,600+

cases seen each year

4

sub-specialized pathologists

Requesting a pathology consult

Our best practices enable expeditious, evidence-based results. Click here to learn more about Mayo Clinic Laboratories consultation request process.

Pathology in Focus

Joseph Maleszewski, M.D., gives an overview of the cardiovascular pathology service and the benefits of collaborating with Mayo Clinic Laboratories.

Expertise

Marie-Christine Aubry, M.D.

Cardiovascular pathologist and professor of Laboratory Medicine and Pathology

Melanie Bois, M.D.

Cardiovascular pathologist and assistant professor of Laboratory Medicine and Pathology

Ying-Chun Lo, M.D., Ph.D.

Cardiovascular pathologist and assistant professor of Laboratory Medicine and Pathology

Joseph Maleszewski, M.D.

Head of Cardiovascular Pathology Section, cardiovascular pathologist, and professor of Laboratory Medicine and Pathology and Medicine

Testing

PATHC | Pathology Consultation

PRKSD | PRKAR1A Full Gene Sequencing and Deletion/Duplication Analysis, Varies

SUDC | Sudden Cardiac Death Pathology Consultation

Amyloidosis

AMPIP | Amyloid Protein Identification, Paraffin, LC-MS/MS

Cardiac neoplasms

MDM2F | MDM2 (12q15) Amplification, Well-Differentiated Liposarcoma/Atypical Lipomatous Tumor, FISH, Tissue

DDITF | Myxoid/Round Cell Liposarcoma, 12q13 (DDIT3 or CHOP) Rearrangement, FISH, Tissue

SS18F | Synovial Sarcoma (SS), 18q11.2 (SS18 or SYT) Rearrangement, FISH, Tissue

Genetic testing

CCMGP | Comprehensive Cardiomyopathy Multi-Gene Panel, Blood

LQTGP | Long QT Syndrome Multi-Gene Panel, Blood

MFRGP | Marfan Syndrome and Related Disorders Multi-Gene Panel, Varies

 PMCMP | Postmortem Cardiomyopathy Panel, Varies

PMARP | Postmortem Arrhythmia Panel, Varies

PMMFR | Postmortem Marfan and Related Panel, Varies

Learn more about how to order these evaluations at your institution.