Understanding the difference between benign and malignant adrenal tumors has always been difficult, but the new Urinary Steroid Profile assay will assist with this medical challenge.
View this week's case study by Justin Juskewitch, M.D., Ph.D.; Mariam (Priya) Alexander, M.D.; and Michael Torbenson, M.D., and make your diagnosis.
This week's Research Roundup highlights thyroid hormone treatment among pregnant women with subclinical hypothyroidism.
Insights gained from algorithms should be shared with clinicians as a way to improve patient care, increase efficiency, and reduce costs.
Vitamin D is essential for the metabolism and stable equilibrium of calcium and phosphate—elements that are necessary for the growth and development of bones and teeth. Vitamin D also aids in the normal functioning of the body’s nervous system. However, in this era of increased supplementation, there is growing evidence that individuals may be at risk of vitamin D toxicity as a result of overdosing.
In this “Hot Topic,” Ravinder Singh, Ph.D., discusses how in this era of increased supplementation, there is growing evidence that individuals may be at risk of vitamin D toxicity as a result of overdosing. The use of multiple products that contain vitamin D supplementation can combine to potentially toxic levels.
In the first comprehensive review article of its kind, a Mayo Clinic fertility consultant describes how evidence for the importance of air quality in clinical embryology laboratories—in particular, the role of volatile organic compounds—has resulted in an evolution of clinical practice that has contributed to improved outcomes. The review was published in the Journal of Assisted Reproduction and Genetics.
Assessing the Measurement of Thyroglobulin in Patients with Differentiated Follicular Cell-Derived Thyroid Carcinoma
To establish the potential impact of mass spectrometry-based Tg quantification on patient care, Mayo Clinic researchers performed a comprehensive analytical and clinical evaluation of immunoassays in thyroid cancer patients. The study, published in the Journal of Clinical Endocrinology and Metabolism, allowed researchers to assess the performance of different serum thyroglobulin assays in the presence of anti-thyroglobulin auto-antibodies.
Serum thyroglobulin concentrations are used to monitor patients with differentiated thyroid cancer, but may be misleading in the presence of antithyroglobulin autoantibodies and heterophile antibodies. Mayo Medical Laboratories has developed an assay to address this issue by testing first for the presence of thyroglobulin antibodies by immunoassay and, in antibody-positive specimens.
Accurate Measurement of Thyroglobulin in the Presence of Interfering Antibodies [Utilization Spotlight]
Serum thyroglobulin (Tg) measurement is used as a follow-up test for patients with differentiated follicular cell-derived thyroid carcinoma after surgical removal of the thyroid. The Mayo Clinic Endocrine Laboratory has developed an assay that allows accurate quantification of Tg in patients with antithyroglobulin autoantibodies or heterophile antibodies.
This new Mayo Clinic assay provides clinicians an accurate measurement of serum thyroglobulin in patients with known or suspected anti-thyroglobulin autoantibodies or heterophilic antibodies. View a quick overview of the test's details and a five-minute video interview with Dr. Stefan Grebe.