MCL

Since overcoming a life-threatening diagnosis five years ago, Jim Smith has embraced life. But each time he travels to Mayo Clinic for follow-up laboratory testing, a well of emotions rises up to remind him of life’s fragility. Thankfully, through streamlined, accurate testing and top-notch clinical care, those feelings are generally short-lived.

In this month's "Hot Topic," Kevin Halling, M.D., Ph.D., discusses new next generation sequencing testing for various tumor types and the rationale for the enhancements that were made; reviews gene additions that are now available in each of the panels; and briefly speaks about the work that was done to validate cytology specimens for use in the subpanels.

Due to the Thanksgiving holiday (recognized on Thursday, November 24th), Mayo Clinic Laboratories' specimen pickup and delivery schedules will be altered. To ensure that your specimen vitality and turnaround times are not affected, plan ahead.

This list includes updates posted to mayocliniclabs.com during the month of October.

In this test specific episode of the "Answers From the Lab" podcast, Ruifeng (Ray) Guo, M.D., Ph.D., explains how Mayo Clinic Laboratories' comprehensive melanoma panel better informs prognosis and treatment.

In the inaugural episode of the "Leveraging the Laboratory" podcast, host Jane Hermansen, outreach manager at Mayo Clinic Laboratories, is joined by outreach colleagues Brianne Newton and Ellen Dijkman Dulkes. They discuss their laboratory backgrounds, the history and importance of laboratory outreach, and how their work can support the growth of hospital laboratories.

Rondell Graham, M.B.B.S., describes Mayo Clinic Laboratories' new colorectal cancer panel. The assay covers more genes to better inform decision-making about prognosis, targeted therapies and a hereditary cancer syndrome.

PACE / State of FL
In this month’s “Virtual Lecture” Bobbi Pritt, M.D., shares a series of spooky tales to scare and amaze related to the discovery, characterization, and clinical presentation of notable viruses.

Ying-Chun Lo, M.D., Ph.D., explains how Mayo Clinic Laboratories' updated lung panel can better guide clinical decision-making, particularly about targeted lung cancer therapies.

In this month's "Hot Topic," David Viswanatha, M.D., discusses updates to Mayo Clinic's next-generation sequencing (NGS) for myeloid neoplasm evaluation, involving new test targets, the rationale for new genetic regions, alignments with the World Health Organization (WHO) guidelines and germline predisposition targets.

In this episode of “Lab Medicine Rounds,” Justin Kreuter, M.D., sits down with Justin Juskewitch, M.D., Ph.D., and Andrew Norgan, M.D., Ph.D., both assistant professors of laboratory medicine and pathology at Mayo Clinic, to talk about informatics for the pathologist.

Andrew McKeon, M.B., B.Ch., M.D., explains how Mayo Clinic Laboratories' pediatric autoimmune/CNS testing can better guide the treatment of autoimmune neurological diseases in children. The tailored evaluation covers only biomarkers relevant to pediatric presentations of the diseases.

This "Pathways" program provides Anatomic and Clinical Pathology cases that include a history, potential answers, rationale, and relevant references. Cases for October include the following sub-specialties: Cardiovascular Pathology, Neuropathology, Pulmonary Pathology, and, Biochemical Genetics.