MCL

Mayo Clinic has launched a first-in-the-U.S. clinical test that will help patients who recently have been diagnosed with an inflammatory demyelinating disease but may be unsure of the exact disorder.

This case presents an unusual colon polyp on an asymptomatic early 70 year-old male. At the time of screening colonoscopy, two small left colon polyps were noted and excised. What is the diagnosis?

Ann Moyer, M.D., Ph.D., discusses an additional gene, NUDT15, which is important in the prediction of thiopurine-related toxicity This gene has been added to our TPMT genotyping assay available through Mayo Medical Laboratories.

In the war against microbes, human beings are vastly outnumbered—and losing the weapons race.

Ultimately, a pathologist has to commit to a diagnosis. Many trainees have difficulty committing to a diagnosis for fear of being wrong. Gary Keeney, M.D., Consultant in the Division of Anatomic Pathology at Mayo Clinic, provides a unique teaching approach with his cases, detailing the ancillary studies and discussing the differential diagnosis of the cases. View case #2.

Devin Oglesbee, Ph.D., Director of the Biochemical and Molecular Genetics Laboratories at Mayo Clinic, provides an overview of the lysosomal storage disease panel, when it is appropriate to order this test, what actions the results allow you to take, and how this test improves upon previous approaches.

In this month’s “Hot Topic,” Alicia Algeciras-Schimnich, Ph.D., will provide you with valuable information regarding the utility of the prostate specific antigen test, and how the calculation of a prostate health index, or phi, can help to stratify a patient’s risk for prostate cancer and reduce unnecessary biopsies.

Teamwork is critical among staff from Mayo Clinic, the Centers for Disease Control and Prevention, Minnesota Department of Health, and the University of Wisconsin-Madison in order to keep tabs on tick trends and defend against vector-borne diseases.

Montana Smith, a student in Mayo Clinic’s Medical Laboratory Science program, reflects on her experience in the program.

Justin Kreuter, M.D., discusses the importance of identifying the "blind spots" in your career and shares some of his own experiences from a patient blood-management conference.

Mike Baisch, Systems Engineer at Mayo Clinic, discusses how to apply the staffing-to-workload methodology to a series of case studies. This post highlights a “basic” staffing model.

Mike Baisch, Systems Engineer at Mayo Clinic, discusses the mechanics of performing a staffing-to-workload analysis in the testing laboratories. There are three primary areas of focus with staffing needs: direct effort, indirect effort, and operational needs. This post focuses on operational needs.

Detection of individuals with low thiopurine methyltransferase (TPMT) activity who are at risk for excessive myelosuppression or severe hematopoietic toxicity when taking thiopurine drugs.