Neurology

Advanced testing at Mayo Clinic Laboratories that confirmed a diagnosis of myasthenia gravis put Lorinda McKinley on the road to renewed health after she nearly lost it all to the rare autoimmune disease.

By Robin Huiras-Carlson • November 1, 2021

John Mills, Ph.D., explains Mayo Clinic Laboratories' new neurofascin 155 (NF155) IgG4 antibody test, which is the first commercially available test in the U.S. to use flow cytometry to detect for NF155 antibodies and confirm diagnosis of CIDP.

By Samantha Rossi • October 5, 2021

Linda Hasadsri, M.D., Ph.D., explains how Mayo Clinic Laboratories’ inclusive approach to mitochondrial disease testing expedites diagnosis. Using innovative methodologies like custom reagents and droplet digital PCR enables precision insights on prognosis and treatment options.

By Samantha Rossi • September 28, 2021

PACE
In this month’s “Virtual Lecture,” Sean Pittock, M.D., discusses the rapidly evolving field of autoimmune neurology helping physicians quickly and accurately diagnose this treatable patient population.

By MCL Education • September 1, 2021

In late 2019, after months of looking for a reason for his rapid loss of muscular function, David Voeltz got an answer: he had necrotizing autoimmune myopathy. Today, after nearly two years of treatment, David has a renewed lease on life and keen appreciation for the Mayo Clinic team that confirmed his diagnosis.

By Robin Huiras-Carlson • August 2, 2021

John Mills, Ph.D., explains Mayo Clinic Laboratories’ approach to MAG antibody testing. The ELISA-based assay uses higher reference ranges and human MAG antigen to detect MAG antibodies, which are associated with a rare, hard-to-treat condition known as DADS neuropathy.

By Samantha Rossi • July 27, 2021

PACE / State of CA / State of FL
This “Specialty Testing” webinar will discuss the collaborative effort which led to the discovery of Kelch like protein 11 (KLHL11) IgG as a specific biomarker of neurological autoimmunity associated testicular germ cell tumor.

By MCL Education • July 22, 2021

In this month’s “Hot Topic,” Sean Pittock, M.D., explains Neuromyelitis Optica Spectrum Disorder (NMOSD) and the critical importance of a sensitive and specific AQP4-IgG laboratory test for early diagnosis and treatment.

By MCL Education • July 5, 2021

Divyanshu (Div) Dubey, M.B.B.S., explains how Mayo Clinic Labs’ new Kelch-11 antibody test — the first in the world — can confirm diagnosis, guide treatment, and improve outcomes in patients affected by testicular cancer-associated paraneoplastic encephalitis.

By Samantha Rossi • June 22, 2021

Mayo Clinic Laboratories has launched a first-in-the-U.S. autoimmune test of the Kelchlike protein 11 antibody, or KLHL11, which is used to detect autoimmune disease associated with testicular cancer.

By Suzanne Ferguson • June 16, 2021

Top highlights include: which insurance companies cover the new Alzheimer's drug, advice on how to talk to someone who is hesitant to get the COVID-19 vaccine, employers requiring you to be vaccinated, FDA approval Alzheimer drug, MN COVID-19 numbers heading in the right direction, having "brain frog" and blaming the pandemic.

By Samantha Rossi • June 11, 2021

In this month’s “Hot Topic,” Andrew McKeon, M.B., B.Ch., M.D., reviews the use of neurological phenotype-based evaluations, the move away from the paraneoplastic evaluation, and upcoming changes to test profiles.

By MCL Education • May 24, 2021

Andrew McKeon, M.B., B.Ch., M.D., discusses updates that are being made to Mayo Clinic Laboratories' autoimmune profile that will remove some antibodies from those profiles. He describes the rationale behind the updates, reviews which antibodies are involved, and explains how the changes will streamline testing and enhance test interpretation.

By Samantha Rossi • April 27, 2021