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Conduct smarter clinical trials with advanced ethanol biomarkers

The scientific toxicology depth you need. The clinical trial support you expect.

Alcohol-related testing plays an essential role in many clinical trials, whether alcohol use is a key endpoint, a critical safety consideration, or a factor in eligibility. Advanced ethanol biomarker testing enables accurate assessment of alcohol use to support clinical trial success.

Mayo Clinic Laboratories BioPharma Diagnostics provides advanced, clinically relevant ethanol biomarker testing. The methodology used in our testing enables detection of even small amounts of ethanol eliminated via nonoxidative pathways into ethyl glucuronide (EtG), ethyl sulfate (EtS), and phosphatidylethanol (PEth). This provides quality data about a subject’s alcohol use that researchers can trust.

Fusing advanced ethanol biomarker testing with deep clinical toxicology expertise and access to interpretive reporting, we bridge the gap between scientifically rigorous testing and industry-ready clinical trials. From alcohol use disorder (AUD) research to safety and drug interaction studies, we deliver the results, data, and services needed for smarter clinical trials.

Interested in strengthening your alcohol-related clinical trial?  Download our ebook to learn how.

"Mayo’s PEth test measures and reports the two most common homologs, which combined account for 60% of all the observed PEth homologs in the blood. The levels correlate with the amount of alcohol consumed in the previous weeks — these levels can be detected in the blood for up to four weeks after excessive alcohol consumption."

Paul Jannetto profile - 2023

Paul Jannetto, Ph.D., co-director of the Clinical Mass Spectrometry Laboratory at Mayo Clinic

Design it right. Validate it right. Run it right.

For clinical trials utilizing ethanol testing, Mayo Clinic Laboratories BioPharma Diagnostics provides end-to-end support that spans biomarker selection, trial design, validation for regulatory filings, operational execution, and expert interpretation. Our advanced ethanol biomarkers are backed by clinical and academic toxicology expertise, a predictable turnaround time, and a dedicated BioPharma Diagnostics professional services team.

Our evidence-based digital guide includes test use case examples to illustrate the utility of alcohol-related biomarkers in clinical trials. Based on existing and prospective clinical trials, the cases highlight the versatility of our ethanol biomarkers in clinical research. Scenarios include:

  • Research focused on alcohol and substance use as an endpoint.
  • The pharmacokinetic impact of alcohol on medication metabolization.
  • Alcohol use as a factor in patient recruitment.

Download now

Fill out the form to download our digital guide on ethanol biomarker testing at Mayo Clinic Laboratories.

Ethanol biomarker testing: Powering research throughout the clinical trial pipeline 


Resources
References
  1. Unpublished Mayo Clinic data