Adrenal disease

Unraveling complex disorders with precision testing

Mayo Clinic Laboratories offers an array of testing designed to detect and characterize adrenal disorders. From screening for adrenal insufficiency to identifying adrenal tumors and evaluating hormonal imbalances, our menu is tailored to provide clinicians with the insights needed to diagnose and treat patients with these complex conditions.

Hereditary movement disorders Test menu

Adrenal insufficiency

Adrenal insufficiency occurs when the adrenal glands make too little cortisol and aldosterone. Our testing measures cortisol and adrenocorticotropic hormone (ACTH) to help guide diagnosis.

Initial testing

Follow-up testing

Advantages

  • Aids in identifying the cause of primary adrenal failure.
  • Provides superior accuracy to clarify uncertain initial testing results through the use of mass spectrometry.
  • Facilitates connection to Mayo Clinic endocrine experts for support interpreting a complex differential diagnosis.

Adrenal cortical carcinoma and adrenal incidentaloma

Adrenal tumors are found incidentally in about 5% of abdominal CT scans. Most of these tumors will turn out to be benign, but a small fraction will be adrenal cortical carcinoma (ACC), a type of cancer with high mortality and frequent recurrence. We offer testing to distinguish between benign or cancerous tumors, the various types of tumors, and tumor activity.

Initial testing

Follow-up testing

Adrenal incidentaloma

Highlights


Congenital adrenal hyperplasia

Congenital adrenal hyperplasia (CAH) encompasses a group of genetic conditions that affect the adrenal glands and result in the inability to make certain hormones, including cortisol, aldosterone, and others. This condition manifests as classic CAH, which is usually found in testing at birth or early infancy, and nonclassic CAH, which may not be found until childhood or early adulthood. Our testing helps diagnose this condition to set patients of any age on the right treatment regimen and monitor treatment efficacy.

Second-tier newborn screening

Genetic testing

Initial testing

Follow-up testing

Treatment monitoring


Cushing syndrome

Cushing syndrome is a condition caused when the adrenal gland produces too much cortisol, and it can only be confirmed by laboratory testing. With symptoms similar to hypertension, obesity, and other common conditions, accurate diagnosis is critical to enable the correct treatment for patients.

Initial testing

Follow-up testing

Highlights

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