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Mayo Clinic Laboratories > Gastroenterology

Integrated, end-to-end gastroenterology testing

Our integration with a world-renowned medical center equips us with patient experience that supports development of disease-specific, algorithmic-based testing approaches that provide faster answers for each patient. Whether screening patients or monitoring therapeutic management, our evaluations cover the full-spectrum of gastroenterology testing.

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Gastroenterology TEST SPECIALTIES

Autoimmune GI dysmotility Autoimmune GI dysmotility
Autoimmune GI dysmotility

Our serological assay for autoimmune GI dysmotility evaluates for antibody biomarkers that can clarify diagnosis and, in some cases, help direct the search for an underlying cancer.

Biopharma testing Biopharma testing
Biopharma testing

With more than 330 tests to confirm diagnosis, monitor disease, and guide therapies, our gastroenterology test menu delivers insights that advance our partners' clinical trials goals. From routine serological testing to advanced biomarker evaluations, our tests are clinically reinforced, cost-effective, and patient-focused.

Celiac disease Celiac disease
Celiac disease

We have established several cascading algorithms to aid in the diagnosis of celiac disease. Automatic reflexing is performed only when necessary to find the right answer for patients and reduce costs.  

Genetic testing Genetic testing
Genetic testing

Our full menu of genetic testing for gastroenterologic disorders includes evaluations that can assist with diagnosis, as well as testing to identify individuals as risk for suboptimal treatment response because of metabolic variation. Built with special attention to testing diversity and equity, our testing helps minimize disparities in healthcare due to genetic makeup.

Inflammatory bowel disease Inflammatory bowel disease
Inflammatory bowel disease

Our robust menu of inflammatory bowel disease (IBD) testing includes calprotectin testing to diagnose IBD or irritable bowel syndrome (IBS); serologic testing to diagnose Crohn’s disease and ulcerative colitis; therapeutic monitoring of thiopurines; genetic testing to identify monogenic IBD; and biologics testing to measure immunogenicity and drug resistance.

Intestinal infections Intestinal infections
Intestinal infections

Our multiplex polymerase chain reaction panel detects the most common agents of bacterial, viral, and parasitic enteric infections directly from stool specimens.

Liver disease Liver disease
Liver disease

We offer a comprehensive menu of liver disease testing to evaluate for metabolic, viral, genetic, autoimmune, and cancerous causes of liver disease.

Malabsorption Malabsorption
Malabsorption

Including evaluations for bile acid malabsorption, pancreatic elastase testing, and disaccharidase testing, our malabsorption test menu can identify underlying causes and direct appropriate treatment. Developed to be as minimally invasive as possible, our malabsorption testing provides clarity on a complex condition.  

Pediatric Pediatric
Pediatric

Developed in collaboration with Mayo Clinic’s top-ranked GI experts, our comprehensive menu of disease-specific tests enables personalized answers to optimize outcomes for the youngest patients.

“Sometimes we can identify a different reason for patients’ symptoms that requires a different treatment course, and that can improve their outcome. When you can actually make a big difference like that, it’s always a test to be proud of.”

Ann Moyer, M.D., Ph.D., co-director of the Personalized Genomics Laboratory

Our difference

Holistic, patient-centered gastroenterology care
Our collaboration with the gastroenterology practice at Mayo Clinic allows us to provide the best possible services and testing for each unique case. From screening to diagnosis and therapeutic monitoring, we offer a comprehensive, one-stop solution for test ordering.

Efficient, clinically meaningful answers
Our data-driven, algorithmic approach to testing ensures patients receive the right test at the right time, which can significantly reduce costs and provide faster answers to patients.

Access to Mayo Clinic expertise
Our testing is backed by some of the world’s leading gastroenterologists. When you partner with us, you gain direct access to Mayo Clinic physicians, laboratorians, and genetic counselors to discuss orders, results, or diagnostic next steps.

News and updates

The latest

A person wearing glasses is looking at DNA results on a computer screen.
Past, Present, and Future Roles of Therapeutic Drug Monitoring in Optimizing Biologic Therapy

April 28, 2025 - Inflammatory bowel disease (IBD) is classified as either Crohn’s disease or ulcerative colitis, based on clinical presentation, endoscopic findings, histopathology, and disease distribution.

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