Autoimmune liver disease
Comprehensive panel to help diagnose the two most common forms of autoimmune liver disease
Autoimmune liver diseases result from inflammatory immune reactions that damage hepatocytes or cholangiocytes. Due to the variance in autoimmune disease forms (which include autoimmune hepatitis [AIH], primary biliary cirrhosis [PBC], and primary sclerosing cholangitis [PSC]), patients can be misdiagnosed. Early and accurate diagnosis can lead to better treatment outcomes for patients, namely, the avoidance of liver transplants.
Our panel evaluates smooth muscle antibodies (SMA), antinuclear antibodies (ANA), and antimitochondrial antibodies (AMA) for patients with suspected autoimmune liver disease, specifically type 1 AIH or PBC, or with liver disease of unknown etiology.