Viral hepatitis

An algorithmic approach to expedite diagnosis

Several laboratory tests may be performed in cases of known or suspected viral hepatitis to help diagnose and monitor patients. Our algorithmic approach to viral test ordering focuses on proper test utilization, taking the guesswork out of test ordering, saving time and money. Developed collaboratively by physicians and laboratorians, our hepatitis-focused algorithms assist with diagnosis, treatment, and monitoring.

To complement our algorithmic test approach and ensure patients have the highest level of care, we offer a comprehensive test menu with more than 40 viral hepatitis-specific tests that includes all aspects of testing, from screening to therapeutic-response monitoring.

Viral hepatitis Test menu

Detection, confirmation, and quantification

The U.S. Preventative Services Task Force recommends one-time screening for HCV infection for adults born between 1945 and 1965 and for those determined to be at high risk for infection. Our reflexive suite of comprehensive testing for the detection and confirmation of both acute and chronic HCV infection enables clarity on disease presence and progression.

Key testing


Unique nucleotide sequences of 5’ noncoding (5’ NC), core, and NS5B regions of the HCV genome allow classification of the virus into six major genotypes or clades (1 to 6). In the United States, the most encountered HCV genotypes/subtypes are 1a and 1b, followed by genotypes 2 and 3. Genotypes worldwide differ based on geographic distribution, disease outcome, and response to antiviral therapy differ. Therefore, reliable methods for genotype determination are important for proper selection of antiviral therapy and optimal patient management, including the use of direct-acting antiviral (DAA) drugs.

Key testing



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