Disaccharidase deficiency

Advanced testing to pinpoint diagnosis

Patients with disaccharidase deficiencies in the duodenum can experience intolerances to foods containing complex sugars, resulting in a range of gastrointestinal symptoms including diarrhea, constipation, abdominal pain and cramping, gas, bloating, and nausea. These common symptoms are frequently misdiagnosed as a food allergy or intolerance.

Disaccharidase deficiency Test menu

Disaccharidase deficiency

Our testing to evaluate patients for disaccharidase deficiency can assist in diagnosis when serological testing, X-ray and ultrasound imaging, and breath testing come back negative. The disaccharides activity panel examines tissue samples, which have been taken as part of endoscopy, to gain quantitative values of lactase, sucrase, maltase, palatinase, and glucoamylase.

Key testing


  • Gold standard for diagnosing disaccharidase deficiencies, which can cause chronic conditions like celiac disease.
  • Measures levels of five naturally occurring digestive enzymes to detect deficiencies that affect carbohydrate absorption.
  • Clinical interpretation of results is provided.



Fill out the form below and one of our specialists will be in touch.