Head and neck pathology

All in one place

Head and neck pathology consultations often relate to the classification of salivary, sinonasal, and oropharynx tumors. Our experts contribute heavily to the clinical practice and are also involved in education, research, and test development.

4,000+

cases seen each year


4

subspecialized pathologists


Requesting a pathology consult

Our best practices enable expeditious, evidence-based results. Click here to learn more about Mayo Clinic Laboratories consultation request process.



Pathology in Focus

David Schembri Wismayer, M.D., gives an overview of the head and neck pathology service and the benefits of testing through Mayo Clinic Laboratories.

Expertise

Joaquin Garcia, M.D.

Head and neck pathologist and professor of Laboratory Medicine and Pathology

Jean Lewis, M.D.

Head and neck pathologist and associate professor of Laboratory Medicine and Pathology

Michael Rivera, M.D.

Head and neck pathologist and assistant professor of Laboratory Medicine and Pathology

David Schembri Wismayer, M.D.

Head of Head and Neck Pathology Section, head and neck pathologist, and assistant professor of Laboratory Medicine and Pathology

Testing

Salivary gland

ETVBF | ETV6 (12p13.2) Rearrangement, FISH
Providing diagnostic and prognostic information for patients with various lymphoid and myeloid malignancies

ETV6F | ETV6 (12p13.2) Rearrangement, FISH, Tissue
Rearrangement supports the diagnosis of secretory carcinoma

EWSF | Ewing Sarcoma (EWS), 22q12 (EWSR1) Rearrangement, FISH, Tissue
Rearrangement supports the diagnosis of clear cell carcinoma

MAMLF | MAML2 (11q21) Rearrangement, Mucoepidermoid Carcinoma (MEC), FISH, Tissue
Rearrangement supports the diagnosis of mucoepidermoid carcinoma

SGTF | MYB (6q23) Rearrangement FISH, Tissue
Rearrangement supports the diagnosis of adenoid cystic carcinoma

Sinonasal

NUT | NUT Immunostain, Technical Component Only
Expression supports the diagnosis of NUT carcinoma

NUTIF | NUTM1 (15q14) Rearrangement, FISH, Tissue
Rearrangement supports the diagnosis of NUT carcinoma

P16 | p16 (INK4a/CDKN2A) Immunostain, Technical Component Only
Overexpression supports the presence of high-risk HPV genotypes

HPVHR | Human Papillomavirus (HPV), High-Risk, DNA In Situ Hybridization
Hybridization supports the presence of high-risk HPV genotypes

HPVE6 | Human Papillomavirus (HPV) High-Risk E6/E7, RNA In Situ Hybridization
Stratification of oropharyngeal squamous cell carcinoma

Oropharynx

P16 | p16 (INK4a/CDKN2A) Immunostain, Technical Component Only
Overexpression supports the presence of high-risk HPV genotypes

HPVHR | Human Papillomavirus (HPV), High-Risk, DNA In Situ Hybridization
Hybridization supports the presence of high-risk HPV genotypes

HPVE6 | Human Papillomavirus (HPV) High-Risk E6/E7, RNA In Situ Hybridization
Stratification of oropharyngeal squamous cell carcinoma

Larynx

HPVHR | Human Papillomavirus (HPV), High-Risk, DNA In Situ Hybridization
Hybridization supports the presence of high-risk HPV genotypes

HPVE6 | Human Papillomavirus (HPV) High-Risk E6/E7, RNA In Situ Hybridization
Stratification of oropharyngeal squamous cell carcinoma

HPVLR | Human Papillomavirus (HPV) Low Risk, DNA In Situ Hybridization
Detection of human papillomavirus (HPV) DNA from low-risk genotypes (6, 11)


Learn more about how to order these evaluations at your institution.