Providing an accurate
diagnosis for patients
Testing to diagnose and manage red blood cell abnormalities
Mayo Clinic’s Metabolic Hematology Laboratory is dedicated to providing accurate diagnoses and clinical interpretations for your patients.
Because the incidence of distinct red blood cell disorders can vary from common to rare, our cases are signed out by board-certified hematopathologists who:
For hematologists whose patients require only a single test, many components of our specialized evaluations can be ordered individually.
By the numbers
profiles for the evaluation of benign hematologic disorders
next-generation sequencing panels specifically created for benign hematology
hemoglobin variants identified with our laboratory testing, with over 45 first described by Mayo Clinic
Benign hematology evaluations
REVE2 | Erythrocytosis Evaluation, Blood
Benign next-generation sequencing assays
Specialized clinical decision-making
Hematopathologists Jennifer Herrick, M.D., James Hoyer, M.D., and Aruna Rangan, M.B.B.S., lead a team with unparalleled depth and breadth of expertise in hemoglobin and red cell disorders. Mayo Clinic’s Metabolic Hematology Laboratory has identified more than 400 hemoglobin variants and described more than 45. The lab’s diagnostic genetic testing results are evaluated by board-certified genetic counselors who specialize in translating genetic information into clinical contexts. Our genetic counselors make their clinical decisions by focusing on the utility and limitations of specific genetic testing methods, familial genetic testing strategies, and genetic variant interpretation, and by identifying potential reproductive risks associated with a test finding.
Webinar — Erythrocytosis
The underlying causes of erythrocytosis (high hemoglobin/hematoctrit) have been progressively elucidated in recent years. The identification of the underlying causes has assumed greater importance with the identification of the JAK2 V617 mutation found in polycythemia vera and other myeloproliferative neoplasms.