In this “Hot Topic,” Joshua Bornhorst, Ph.D., assistant professor of laboratory medicine and pathology at Mayo Clinic, reviews biomarker component testing for hepatocellular carcinoma, explains the GALAD score, and explores GALAD score testing at Mayo Clinic Laboratories.

In this “Hot Topic,” Paul Jannetto, Ph.D., highlights Mayo Clinic’s targeted benzodiazepine assay and discusses the advantages and limitations of various urine-screening assays as well as quantitative confirmatory testing to determine compliance to benzodiazepine therapy.

PACE / State of FLThis month’s “Virtual Lecture,” discusses how artificial intelligence can be utilized to classify kidney stones while demonstrating improvement in quality and patient safety.

In this month's "Hot Topic," Bobbi Pritt, M.D., describes the challenges to traditional microscopy for the detection of protozoa in stool specimens, lists potential uses of artificial intelligence in parasite detection, and discusses workflow modifications that may be needed when implementing digital slide scanning and AI-assisted interpretation.

PACE / State of FLIn this month’s “Virtual Lecture” Mark Hyde continues to share what he has learned during his 28 years of workplace consulting experience and counseling with thousands of employees concerning work topics such as stress, fatigue, burnout, retention, and joy. Both personal and workplace resilience concepts and strategies will be highlighted to maintain a healthy sense of well-being and joy.

In this month's "Hot Topic," David Murray, M.D., Ph.D., reviews the role of urine testing for monoclonal gammopathies and discusses Mayo Clinic’s use of MASSFIX to replace traditional immunofixation testing.

In this month's "Hot Topic," Eoin Flanagan, M.B., B.Ch., reviews the recent diagnostic criteria for Myelin Oligodendrocyte Glycoprotein Antibody-associated Disease (MOGAD).

In this “Hot Topic,” Paul Jannetto, Ph.D., highlights Mayo Clinic Laboratories’ AI-augmented kidney stone test and discusses the proper procedures for collecting and processing kidney stones to provide accurate, cost-effective analysis of patients’ kidney stones in a timely manner.

In this "Hot Topic," Melissa Snyder, Ph.D., provides a brief review of published guidelines for the diagnosis of celiac disease, with a specific focus on the role of laboratory testing.

In this month's "Hot Topic," Christopher Klein, M.D., and Zhiyv (Neal) Niu, Ph.D., discuss how Mayo Clinic’s neuropathy and neuromuscular gene panels have enhanced patient care.

In this month's "Hot Topic," Eoin Flanagan, M.B., B. Ch., discusses the important issue of autoimmune encephalitis misdiagnosis and identifies red flags that be useful in clinical practice to suggest alternative diagnoses and highlight antibodies that sometimes cause confusion.

In this month's "Hot Topic," Elitza Theel, Ph.D., shares the recommended approach to serologic testing for assessment or infection with coccidioides.