Ordering this test is helpful for establishing an individual’s risk or determining whether a residual risk remains. Specific ordering scenarios include:

• Patients with established coronary artery disease.
• Patients with history of, or clinical suspicion for, acute coronary syndrome or myocardial infarctions.
• Patients with intermediate or undetermined atherosclerotic cardiovascular risk, as 19.4% cardiovascular events occur in the absence of traditional risk factors.