Mayo Clinic Laboratories > Neurology > Autoimmune > Dementia

Autoimmune dementia

Identifying a possibly reversible course

Misdiagnosis of autoimmune dementia as an irreversible progressive neurodegenerative disorder may delay a correct diagnosis beyond the window of reversibility (6–12 months) and result in devastating consequences for the patient and family. Accurate diagnosis and early-initiated immunotherapy give patients the best possible outcome.

35%

35% of MAYO CLINIC PATIENTS DIAGNOSED WITH AND TREATED FOR AN AUTOIMMUNE DEMENTIA WERE INITIALLY MISDIAGNOSED AS HAVING A NEURODEGENERATIVE DISORDER

DEMENTIA Test menu

Dementia Dementia

Dementia

Key testing

Advantages

  • Uses a reflexive, algorithmic approach and multiple methodologies, including indirect immunofluorescence assay (IFA), cell-binding assay, immunoblot, radioimmunoassay, and Western blot to detect for nearly 20 neural antibodies associated with autoimmune dementia.
  • Positive test results facilitate selection of targeted immunotherapies.
Learn more Our evolving approach to autoimmune neurology testing uses phenotype-specific evaluations that include multiple antibodies known for their disease associations.
Learn more Antibody prevalence in epilepsy and encephalopathy (APE2) score.

Highlights

Updates Streamline Autoimmune Neurology Testing: Anastasia Zekeridou, M.D., Ph.D.

Anastasia Zekeridou, M.D., Ph.D., explains how Mayo Clinic Laboratories' updated panels and methodology boost the accuracy and efficiency of testing for three autoimmune neurology biomarkers. Early diagnosis is key to managing debilitating conditions associated with these antibodies.

Learn more
Tests Aid Diagnosis of Cancer-Associated Neurological Disorders: Divyanshu Dubey, M.B.B.S.

Divyanshu Dubey, M.B.B.S., explains how Mayo Clinic Laboratories' unique PDE10A and TRIM46 tests facilitate the management of central nervous system disorders triggered by cancers. Early diagnosis and treatment are important for managing disabling neurological symptoms and malignancy.

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