Confirm and clarify diagnosis
Individualized insights for tailored treatment
Ataxia, which involves poor muscle control that may cause difficulty with walking, balance, hand coordination, speech, and swallowing, results from damage to the cerebellum. While the condition can be caused by alcohol misuse, stroke, tumor, multiple sclerosis, and certain medications, it also has genetic causes.
Inherited forms of ataxia can be autosomal dominant or autosomal recessive, with different genetic variants causing different types — most of which are progressive.
Mayo Clinic Laboratories’ full menu of hereditary ataxia testing includes a comprehensive panel that evaluates 198 genes associated with the disorder. In addition, we offer focused panels that evaluate for Friedreich’s ataxia and spinocerebellar ataxia, which are among the most common forms of inherited disease. In addition to molecular testing for Friedrich’s ataxia, we offer biochemical testing for frataxin protein analysis.
ATAXP | Inherited Ataxia Gene Panel, Varies
FFRWB | Friedreich Ataxia, Frataxin, Quantitative, Blood
AFXN | Friedreich Ataxia, Repeat Expansion Analysis, Varies
SCAP | Spinocerebellar Ataxia Repeat Expansion Panel, Varies
SCARA | Spinocerebellar Ataxia Type 1, 2, 3, 6, or 7, Repeat Expansion Analysis, Varies
ISPP | Inherited Spastic Paraplegia Gene Panel, Varies
HAD | Huntington Disease, Molecular Analysis, Varies