Pulmonary pathology
All in one place
Our pathology section at Mayo Clinic represents the largest group of pulmonary pathologists in the country. We see a broad range of neoplastic and non-neoplastic thoracic cases and have access to additional testing for an in-depth workup of cases, including predictive markers for lung cancer and molecular testing.
Mayo Clinic is the first center accredited by the Primary Ciliary Dyskinesia Foundation for the diagnosis of primary ciliary dyskinesia, a rare and debilitating lung disease. Read more about how our electron microscopy testing and expert pathologist interpretation aid in the diagnosis of this disease.
Pulmonary pathology Test menu
Pathology consultations
Key testing
Immunohistochemical stains
Key testing
- ALKD5 | Anaplastic Lymphoma Kinase (ALK[D5F3]) Immunostain, Technical Component Only
- ASCL1 | Achaete-Scute Homolog 1 (ACSL1) Immunostain, Technical Component Only
- BRAFV | BRAF V600E Immunostain, Technical Component Only
- DESG3 | Desmoglein 3 (DSG3) Immunostain, Technical Component Only
- NUT | NUT Immunostain, Technical Component Only
- P40 | p40 Immunostain, Technical Component Only
- P40NA | p40 + Napsin A Immunostain, Technical Component Only
- TTF40 | TTF41 (SPT24) + p40 Immunostain, Technical Component Only
- INI1 | Integrase Interactor 1 (INI1/BAF47) Immunostain, Technical Component Only
- BRG1 | BRG1 (SMARCA4) Immunostain, Technical Component Only
- SP263 | Programmed Death-Ligand 1 (PD-L1) (SP263), Semi-Quantitative Immunohistochemistry, Manual
- SP142 | Programmed Death-Ligand 1 (PD-L1) (SP142), Semi-Quantitative Immunohistochemistry, Manual
- 22C3 | Programmed Death-Ligand 1 (PD-L1) (22C3), Semi-Quantitative Immunohistochemistry, Manual
Malignant mesothelioma
Key testing
- BAP1 | BAP1 Immunostain, Technical Component Only
- MTAP | Methylthioadenosine Phosphorylase (MTAP) Immunostain, Tech Only
Molecular testing
Key testing
- MCLNG | MayoComplete Lung Cancer-Targeted Gene Panel with Rearrangement, Tumor
- MCLNR | MayoComplete Lung Rearrangements, Rapid, Tumor
- EGFRW | EGFR Targeted Mutation Analysis with ALK Reflex, Tumor
- LCAF | Lung Cancer, ALK (2p23) Rearrangement, FISH, Tissue
- RETF | Lung Cancer, RET (10q11) Rearrangement, FISH, Tissue
- ROS1F | Lung Cancer, ROS1 (6q22) Rearrangement, FISH, Tissue
- METF | MET (7q31), FISH, Tissue
- FGF1F | FGFR1 (8p11.2) Amplification, FISH, Tissue
- NTRK | NTRK Gene Fusion Panel, Tumor
Soft tissue tumors in thorax
Key testing
- STAT6 | Signal Transducer and Activator of Transcription 6 (STAT6), Technical Component Only
- SOX10 | SOX10 Immunostain, Technical Component Only
- SDHB | SDHB Immunostain, Technical Component Only
- SS18F | Synovial Sarcoma (SS), 18q11.2 (SS18 or SYT) Rearrangement, FISH, Tissue
- ALKD5 | Anaplastic Lymphoma Kinase (ALK[D5F3]) Immunostain, Technical Component Only
- EWSF | Ewing Sarcoma (EWS), 22q12 (EWSR1) Rearrangement, FISH, Tissue
- FUSI | FUS Immunostain, Technical Component Only
- MDM2F | MDM2 (12q15) Amplification, Well-Differentiated Liposarcoma/Atypical Lipomatous Tumor, FISH, Tissue
- DDITF | Myxoid/Round Cell Liposarcoma, 12q13 (DDIT3 or CHOP) Rearrangement, FISH, Tissue
Thymic epithelial tumors
Key testing