Initiate earlier treatment

Pulmonary renal syndrome (PRS) is characterized by rapidly progressive glomerulonephritis (RPGN) and diffuse alveolar hemorrhage secondary to an autoimmune response. The most common causes of PRS in adults are ANCA-associated vasculitis (AAV) and anti-GBM disease. Due to the overlap in clinical presentation, frequency of RPGN, and the need for early diagnosis and treatment, testing for ANCA and anti-GBM is recommended during the differential diagnosis.

Glomerulonephritis test menu


Prompt identification of ANCA and anti-GBM antibodies allows for early initiation of treatment and may improve patient outcomes. Antibodies to GBM antigens cause glomerulonephritis, Goodpasture’s syndrome, and, less commonly, pulmonary hemosiderosis. Anti-neutrophil cytoplasmic antibodies occur in various types of autoimmune diseases including renal limited vasculitis (e.g., Wegener’s granulomatosis [WG] or microscopic polyangiitis [MPA]) and pauci-immune necrotizing GN.1 Comprehensive testing, prompt result reporting, and access to more than 150 years of advanced medical knowledge deliver the answers your practice needs to keep care local.

Key testing


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