Post-transplant testing
Guiding patient recovery after kidney transplant
For patients who’ve undergone kidney transplantation, laboratory testing plays an essential role in both short- and long-term success. Our full menu of guidelines-backed testing supports patients throughout recovery, equipping nephrologists and other care providers with critical insights to guide and monitor treatment, assess organ health, and address problems when they arise.
POST-TRANSPLANT TEST MENU
Infectious diseases
The immunocompromised status of post-transplant patients requires diligent attention to the presence of infectious pathogens, since even common infections can lead to life-threatening symptoms. We offer a wide range of infectious disease testing to assist physicians in identifying infectious diseases and selecting appropriate treatment.
Key testing
- ADVQU | Adenovirus DNA Detection and Quantification, Plasma
- CMVQN | Cytomegalovirus (CMV) DNA Detection and Quantification by Real-Time PCR, Plasma
- EBVQN | Epstein-Barr Virus DNA Detection and Quantification, Plasma
- HCSRN | Hepatitis C Virus (HCV) Antibody Screen with Reflex to HCV RNA, PCR, Asymptomatic, Serum
- PBKQN | BK Virus DNA Detection and Quantification, Plasma
Additional tests
- CMVG | Cytomegalovirus (CMV) Antibodies, IgG, Serum
- CMVQN | Cytomegalovirus (CMV) DNA Detection and Quantification by Real-Time PCR, Plasma
- EBVAB | Epstein-Barr Virus Antibody Profile, Serum
- EBVPV | Epstein-Barr Virus (EBV), Molecular Detection, PCR, Varies
- EBVQN | Epstein-Barr Virus DNA Detection and Quantification, Plasma
- HBAB | Hepatitis B Virus Surface Antibody, Qualitative/Quantitative, Serum
- HBAG | Hepatitis B Virus Surface Antigen, Serum
- HBCSN | Hepatitis B Virus Core Total Antibodies Screen, Serum
- HBVQN | Hepatitis B Virus (HBV) DNA Detection and Quantification by Real-Time PCR, Serum
- HIS12 | HIV-1/HIV-2 RNA Detection, Serum
- PBKQN | BK Virus DNA Detection and Quantification, Plasma
- QHV6P | Human Herpesvirus-6 A and B DNA Detection and Quantification, PCR, Plasma
- STRNG | Strongyloides Antibody, IgG, Serum
- TCD4 | CD4 Count for Immune Monitoring, Blood
- TXMGP | Toxoplasma gondii Antibody, IgM and IgG, Serum
- UBKQN | BK Virus DNA Detection and Quantification, Random, Urine
Highlights
Joseph Yao, M.D., explains how Mayo Clinic Laboratories' new quantitative assay (Mayo ID: ADVQU) goes beyond qualitative testing to evaluate transplant patients for adenovirus infection. Adenovirus can cause life-threatening disease in immunocompromised transplant patients, especially children.
Elitza Theel, Ph.D., explains how Mayo Clinic Laboratories' unique Histoplasma/Blastomyces test provides cost-effective evaluation for fungal infections that cause pulmonary illness. The assay reliably detects both Histoplasma and Blastomyces pathogens in a single test.
In this month's "Hot Topic," Elitza Theel, Ph.D., shares the recommended approach to serologic testing for assessment or infection with coccidioides.
Kidney function
Following a kidney transplant, ongoing assessment of kidney function through cystatin C testing offers reliable, accurate answers on kidney health. Serum cystatin C is a well-established biomarker of kidney function and an alternative to creatinine testing.
Key testing
Additional tests
- ALB | Albumin, Serum
- ALB24 | Albumin, 24 Hour, Urine
- CRCL | Creatinine Clearance, Serum and 24-Hour Urine
- CRTS1 | Creatinine with Estimated Glomerular Filtration Rate (eGFR), Serum
- CTU | Creatinine, 24 Hour, Urine
- POXA1 | Oxalate, Plasma
- PTU | Protein, Total, 24 Hour, Urine
- RCTUR | Creatinine, Random, Urine
- RFAMA | Renal Function Panel, Serum
Liver function
Identifying irregularities in liver function in patients who’ve undergone kidney transplant can help with post-operative management as well as enable early interventions in cases when liver enzymes become elevated. We offer several tests that measure liver function to help identify potential issues before problems arise.
Testing
- ALKP | Alkaline Phosphatase, Total and Isoenzymes, Serum
- ALP | Alkaline Phosphatase, Serum
- ALT | Alanine Aminotransferase (ALT) (GPT), Serum
- AST | Aspartate Aminotransferase (AST) (GOT), Serum
- BILI3 | Bilirubin, Serum
- BILID | Bilirubin Direct, Serum
- BILIT | Bilirubin, Total, Serum
- LIVPR | Liver Profile, Serum
Metabolic
Our robust metabolic test offerings can provide valuable insights on metabolic changes and assist with early detection and management of certain risks and complications, such as metabolic syndrome and metabolic acidosis.
Testing
- 25HDN | 25-Hydroxyvitamin D2 and D3, Serum
- BUN | Blood Urea Nitrogen (BUN), Serum
- CA | Calcium, Total, Serum
- CAI | Calcium, Ionized, Serum
- CL | Chloride, Serum
- ELPSR | Electrolyte Panel, Serum
- GLURA | Glucose, Random, Serum
- HCO3 | Bicarbonate, Serum
- KS | Potassium, Serum
- MGS | Magnesium, Serum
- NAS | Sodium, Serum
- PHOS | Phosphorus (Inorganic), Serum
- PTH2 | Parathyroid Hormone, Serum
Pharmacogenomic
Among patients who’ve undergone kidney transplant, pharmacogenomic (PGx) testing enables a personalized approach to medication selection. Preemptive PGx testing is a valuable tool to optimize levels of certain medications, such as tacrolimus.
Key testing
Highlights
Jessica Wright, Pharm.D., BCACP, explains how Mayo Clinic Laboratories' 3A5Q test helps determine initial tacrolimus doses for individuals after non-liver organ transplants. Optimal tacrolimus levels are one of the important factors in survival of the transplanted organ.
Ann Moyer, M.D., Ph.D., explains Mayo Clinic Labs’ new focused pharmacogenomics panel, a real-time, PCR-based testing approach that assesses 10 genes known for their drug-gene associations, to provide guidance on medication selection for patients across a variety of specialities.
Therapeutic Drug Monitoring
Including testing for tacrolimus and cyclosporine, among others, our therapeutic drug monitoring menu can clarify treatment efficacy in kidney transplant patients. Medication monitoring in patients supports appropriate dosing and helps to manage the risk of organ rejection.